Protein Info for HMPREF1078_RS00545 in Parabacteroides merdae CL09T00C40

Annotation: metallophosphoesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 268 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF00149: Metallophos" amino acids 54 to 226 (173 residues), 46.6 bits, see alignment E=2.9e-16

Best Hits

KEGG orthology group: None (inferred from 73% identity to pdi:BDI_1215)

Predicted SEED Role

"putative calcineurin superfamily phosphohydrolase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (268 amino acids)

>HMPREF1078_RS00545 metallophosphoesterase (Parabacteroides merdae CL09T00C40)
MYKQTLPLFLCIFLSACDLIDYHPYDGRLTISERDINDHNIPLIEAATKDKDTIRFVLMG
DTQRSYDETEDFVKHINTKKDSIDFIIHGGDYTEFGMKKEYEWTVNILSKLDIPYVGLIG
NHDVIGNGDQVFNKLFGEENFSFIVRDVKFVCLNTNAIEYDYSHPVPDFGFLKEELQDST
RHYSRTIVAMHARPGSEQFDNNVKDVFQLYIREFPSLLFCLNAHNHQLQVEDLFDDGIIY
YGCSNIAKRNYLLFTLTPDGYTYEIINF