Protein Info for HMPREF1078_RS00305 in Parabacteroides merdae CL09T00C40

Annotation: family 20 glycosylhydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 724 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF02838: Glyco_hydro_20b" amino acids 72 to 122 (51 residues), 51.4 bits, see alignment 3.5e-17 PF00728: Glyco_hydro_20" amino acids 126 to 470 (345 residues), 406.3 bits, see alignment E=2.6e-125 PF13290: CHB_HEX_C_1" amino acids 516 to 566 (51 residues), 47.9 bits, see alignment 2.2e-16 PF13287: Fn3_assoc" amino acids 521 to 574 (54 residues), 42.8 bits, see alignment 9.1e-15

Best Hits

KEGG orthology group: K12373, hexosaminidase [EC: 3.2.1.52] (inferred from 79% identity to pdi:BDI_0665)

Predicted SEED Role

"Beta-hexosaminidase (EC 3.2.1.52)" in subsystem Chitin and N-acetylglucosamine utilization or N-Acetyl-Galactosamine and Galactosamine Utilization (EC 3.2.1.52)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.52

Use Curated BLAST to search for 3.2.1.52

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (724 amino acids)

>HMPREF1078_RS00305 family 20 glycosylhydrolase (Parabacteroides merdae CL09T00C40)
MLLPKQSRNCVTGLAAACSLLLIACSPEEVRQVNLIPKPEQMTMTGGTFTVDSLALFGGQ
SSRNIKTVIDEAWSGNPEGYQLDVTPGGIDLRAGSPDGLFYGMQTLRQLYAGGEVPCVSI
RDNPRFGYRGLHLDVSRHFFSKEEVMKLLDVMSFYKLNTLHMHLTDAGGWRIEIDKYPKL
TSETAFRTESDWRKWWDGRDRKYLPEGTPGAYGGYYTKEDIREIVKHAASKHINIIPEIE
FPGHSEEVLMAYPELSCSGKPYQNGDFCIGNEQSFTFMEDVLAEVIDLFPSEYIHVGGDE
AGKSAWKKCPKCQALMKKNGMKSVDELQSYMIHRAEEFLNSKDRRLIGWDEILEGGLAPE
ATVMSWRGEDGGIKAARMGHDVVMTPGNYMYLDFYQADPKTQPYAIGGYTPIKKVYSYDP
VPADSLTVEECRHILGVQANTWTEYIQTPEHLEYMMFPRALAVAEIGWTSQELRTWEDFK
PRMNAHISKLQGMGIRTFTLSDELEVTMQVDTAGREIEVILDAEKYPAEIRYTTDGSVPV
ASSALYAGPITVQDSAHIKAAIFRDGVLQGTPTEKKVDYHRAINKPIHYNSKLYEGYMAG
GTNALLDGYRGGLTYLDGRWQGYLDDLDCVIDMEEDTDIHKVSIRFMQLIGPGVFQPGQV
ELLTSEDGENFISRGIVPTTVPADDPDLLFQEYTFDGNWKTRYIRLKAPRANPGFIFADE
IVVW