Protein Info for HMPREF1078_RS00035 in Parabacteroides merdae CL09T00C40

Annotation: Maf-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 196 TIGR00172: septum formation protein Maf" amino acids 10 to 194 (185 residues), 150.4 bits, see alignment E=2e-48 PF02545: Maf" amino acids 12 to 196 (185 residues), 205.8 bits, see alignment E=2.4e-65

Best Hits

Swiss-Prot: 71% identical to NTPPA_PARD8: dTTP/UTP pyrophosphatase (BDI_0169) from Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)

KEGG orthology group: K06287, septum formation protein (inferred from 71% identity to pdi:BDI_0169)

Predicted SEED Role

"Septum formation protein Maf" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (196 amino acids)

>HMPREF1078_RS00035 Maf-like protein (Parabacteroides merdae CL09T00C40)
MKSILPNLSQYKIVLGSNSPRRRELLAGLDIDFEVQTIPDIDESFPKTLRSDEVPVYIAR
KKAEAYISSMSADELLITADTIVWTFSEILGKPKDREDAIAMLRKLSGHVHEVITGVCIT
TKEKTVSFSASSTVCFARLDDDEIVYYVDKYRPFDKAGSYGIQEWIGYVAVEAINGSFYN
VMGLPVRLLYQELKKF