Protein Info for HMPREF1078_RS00015 in Parabacteroides merdae CL09T00C40

Annotation: efflux transporter outer membrane subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 456 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 13 to 454 (442 residues), 322 bits, see alignment E=3.3e-100 PF02321: OEP" amino acids 60 to 246 (187 residues), 73.5 bits, see alignment E=9.9e-25 amino acids 272 to 452 (181 residues), 103.8 bits, see alignment E=5e-34

Best Hits

KEGG orthology group: None (inferred from 70% identity to pdi:BDI_1491)

Predicted SEED Role

"RND efflux system, outer membrane lipoprotein CmeC" in subsystem Multidrug Resistance Efflux Pumps or Multidrug efflux pump in Campylobacter jejuni (CmeABC operon)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (456 amino acids)

>HMPREF1078_RS00015 efflux transporter outer membrane subunit (Parabacteroides merdae CL09T00C40)
MKRNIYIFIVLSLALALPSCKIGKKYARPELDLPEEIVAGADTASIDSISWQSLYVDTTL
QRLITIALDNNKDMKIAVAKVKEMIASKRITFADQFPEIGARIYGQKERLNYGGDNPKPD
SEYGAKLALSWELDLWGNLRWANEAGIAAYLQSVEARHALQMTLVAEVAAAYYELCALDQ
EQDIVRHTLAARREGVRLAKLRFEGGLTSETSYSQAQVELARTETLLPSLEQKIKIKEND
LAFLLGQYSGDIPRGLPLREQHLLETLPVGLPSSLLERRPDMRQAEQKLREANAGVGVAQ
TDLFPKISLTGNLGFENEELTNFIKSPAWFLAGDLLQPLFAMGKNKAKLKAARARYEQEV
YNYQKSVLSVFKEVNNAIVTIRKAKEVRMSYEKLLNAADTYLQLAQLQYINGVTSYMDVL
DAQRGLLDAQLSLNKAMLDELLSTVYLYKALGGGWE