Protein Info for HMPREF1058_RS18385 in Phocaeicola vulgatus CL09T03C04

Annotation: alpha-xylosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 748 PF13802: Gal_mutarotas_2" amino acids 68 to 259 (192 residues), 61.6 bits, see alignment E=2e-20 PF01055: Glyco_hydro_31_2nd" amino acids 304 to 619 (316 residues), 287.9 bits, see alignment E=1.8e-89 PF21365: Glyco_hydro_31_3rd" amino acids 629 to 715 (87 residues), 91.5 bits, see alignment E=5.8e-30

Best Hits

KEGG orthology group: K01811, putative family 31 glucosidase (inferred from 100% identity to bvu:BVU_2931)

Predicted SEED Role

"Alpha-xylosidase (EC 3.2.1.-)" in subsystem Xylose utilization (EC 3.2.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.-

Use Curated BLAST to search for 3.2.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9UM93 at UniProt or InterPro

Protein Sequence (748 amino acids)

>HMPREF1058_RS18385 alpha-xylosidase (Phocaeicola vulgatus CL09T03C04)
MKPTNYHLFDFLDFDPDLSRDESLWKAYKPTSVYEKDGDICINVPFQKQVLSNDMAPDTT
SPREEYTLVIRQYTSGITRLFIGFGEESMTDQSEMLQFSDRVKKLPLQVTQTEGEWLITT
QDGIQRALIHVKPPVLDRWSELLPDPQETLDLRLYPDGKREIRLAAYDHFSPPRYDALPL
AFCKRNGVKERATLSFESKPDECFAGTGERFAKMDLSGQTFFLKNQDGQGVNNRRTYKNI
PFYLSSRMYGTFYHTCAHSKLSLAGQSTRSVQFLSDQAMLDVFVIAGDTMEEILRGYRDL
TGYPSMPPLWSFGIWMSRMTYFSADEVNEICDRMRAEHYPCDVIHLDTGWFKTDWLCEWK
FNEERFPDPKGFIQGLKKKGYRVSLWQLPYVAENAEQIDEARKNDYIAPLTKKQDSEGSN
FSALDYAGTIDFTYPKATEWYKGLLKNLLDMGVTCIKTDFGENIHMDALYKGMKPELLNN
LYALLYQKAAYEITKDVTGDGIVWARSAWAGCQRYPLHWGGDSCSSWDGMAGSLKGGLHF
GLSGFAFWSHDVPGFHTLPNFMNSIVDDDVYMRWTQFGVFSSHIRYHGTNKREPWHYPAI
APMIKKWWKLRYTLIPYIVEQSRKAIASGAPLLQALIFHHPEDKLCWHIDDEYYFGNDFL
VAPVMNSENRRDVYLPEGKWVNFFTGERLEGGRWLKNLDIPLDEMPVYVRQGATIPVYPD
EVECTDDMDLSKSIGLHIDPHFKGIFKN