Protein Info for HMPREF1058_RS18065 in Phocaeicola vulgatus CL09T03C04

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 247 PF00005: ABC_tran" amino acids 24 to 173 (150 residues), 120.5 bits, see alignment E=4.4e-39

Best Hits

Swiss-Prot: 59% identical to Y352_THEMA: Uncharacterized ABC transporter ATP-binding protein TM_0352 (TM_0352) from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

KEGG orthology group: K02003, (no description) (inferred from 100% identity to bvu:BVU_2802)

MetaCyc: 45% identical to lipoprotein release complex - ATP binding subunit (Escherichia coli K-12 substr. MG1655)
RXN-22427

Predicted SEED Role

"ABC transporter ATP-binding protein"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9A5S7 at UniProt or InterPro

Protein Sequence (247 amino acids)

>HMPREF1058_RS18065 ABC transporter ATP-binding protein (Phocaeicola vulgatus CL09T03C04)
MKKIIELQNIKRNFQVGDETVHALRGISFTIYEGEFVTIMGTSGSGKSTLLNTLGCLDTP
TSGEYLLDGVSVRTMSKPQRAVLRNRKIGFVFQNYNLLPKTTAVENVELPLMYNSSVSAS
ERRKRAIESLIAVGLGDRLEHKSNQMSGGQMQRVAIARALVNNPAVILADEATGNLDTRT
SFEILVLFQKLHAEGRTLIFVTHNPEIAQYSSRNIRLRDGHVVEDTINPQILSAAAALAA
LPKNDED