Protein Info for HMPREF1058_RS17725 in Phocaeicola vulgatus CL09T03C04
Annotation: hypothetical protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
No protein families (PFam or TIGRFam), signal peptides, or transmembrane helices were found in this protein.
Best Hits
KEGG orthology group: K01843, lysine 2,3-aminomutase [EC: 5.4.3.2] (inferred from 98% identity to bvu:BVU_2729)Predicted SEED Role
"Lysine 2,3-aminomutase (EC 5.4.3.2)" in subsystem Lysine degradation (EC 5.4.3.2)
MetaCyc Pathways
- L-lysine fermentation to acetate and butanoate (3/10 steps found)
- superpathway of L-lysine degradation (6/43 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 5.4.3.2
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See I9J9D5 at UniProt or InterPro
Protein Sequence (703 amino acids)
>HMPREF1058_RS17725 hypothetical protein (Phocaeicola vulgatus CL09T03C04) MKQKNKMLSTHGIKTLFETRLTQLTSLASESQDETAFKNKLNDYLLSGPIYNPTAARQIK RLIDNDGKTIYEASTEQEIKIETISLLWKFLTNRIINEEISVDLWIDLYHQFDRLHHEEE ELPDEKQVQQWMKRWPSGLNEDVRGIRRQNKERIISLLIQKIENRHAPSSRYLFPEGSTE EDKRRLVCQWWNEARFHLAMAVKSPTELNRMLGNSLSEETLQLYHKARKKGMPVFITPYY LSLLNPTGKGYDDEAIRSYILYSSQLVETYGNIHAWEKEDAVEDGKPNAAGWLLPDGHNI HRRYPDVAILIPDSMGRACGGLCASCQRMYDFQSERLNFNFEELKPKESWDKRLRKLMEY FENDTQLRDILITGGDALMSQNKTLRNILEAVYKMAVRKRNANLQRAEGEKYAELQRVRL GSRLPVYLPMRINDELLDILREFKEKASAVGVSQFLIQTHFQTPLEVTPEAREAIRKILA AGWTITNQLVYNVAASRRGHTAKLRKVLNGLGVLCYYTFSVKGFEENYAVFAPNSRSLQE KEEEKVWGKLSAEQEKEFLNLLRNSKDRAAAVQRFCTFHQIPFVATDRSVLNLPGIGKSM TFVTIGMTKEGKRILEFDHDPTRQHSPIIHQMEKIYIKENKSIWQYMLQLQEMGEKKEEY ASLWKYMEGETEHRFPLYNYPDPGFRITEKYSHLSVVGNKSIC