Protein Info for HMPREF1058_RS15420 in Phocaeicola vulgatus CL09T03C04

Annotation: peptidase S41

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 465 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF18294: Pept_S41_N" amino acids 34 to 86 (53 residues), 52.6 bits, see alignment 3.5e-18 PF03572: Peptidase_S41" amino acids 217 to 401 (185 residues), 72.8 bits, see alignment E=2.6e-24

Best Hits

KEGG orthology group: None (inferred from 99% identity to bvu:BVU_2263)

Predicted SEED Role

"Carboxyl-terminal protease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9A2Q8 at UniProt or InterPro

Protein Sequence (465 amino acids)

>HMPREF1058_RS15420 peptidase S41 (Phocaeicola vulgatus CL09T03C04)
MKHIRSTFFLLTTLFIMASCGEDRSGEYYALIGENVWIEQIMKEHYLWYDSIPAIKETDY
FAEPEDFLQKLVYIKAQNGKGDPYSYIEIKDASDAARSYLQRTSTYGFDFELMTDPTGIS
SHVFARILFVLPNSPASEAGLERGNWISAIGKEELTNNNYGYLMEGGNTTFARESLVFDE
EGNSSWIATDTVKVAASRPVELNPFYIDTVYEVSEKKIAYMVYNEFSTGPNNQATDTEYR
EQMKQIFARFKGQSPDAFILDLRYNPGGYLSCATDLGSYLAPAADLGKVFCTTLYNDISD
PQKIDFPLNTGLASENLNLSKLYVLTSKFTASASEAVINCLRPYIGTENVVVIGETTVGK
NVAMEPYQDERYNFILWPVVAYVLNSAGQANYVNGITPDFTLSERNLISPLYPLGDTKEY
LLKNTIAYITTGNMPDLPQTEEQVSKGKIIYNSLIRRSMNGIRLR