Protein Info for HMPREF1058_RS15350 in Phocaeicola vulgatus CL09T03C04

Annotation: DNA polymerase III subunit gamma/tau

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 603 TIGR02397: DNA polymerase III, subunit gamma and tau" amino acids 4 to 359 (356 residues), 449.7 bits, see alignment E=4.2e-139 PF13177: DNA_pol3_delta2" amino acids 22 to 179 (158 residues), 158 bits, see alignment E=5.3e-50 PF00004: AAA" amino acids 43 to 174 (132 residues), 47 bits, see alignment E=8.8e-16

Best Hits

KEGG orthology group: K02343, DNA polymerase III subunit gamma/tau [EC: 2.7.7.7] (inferred from 100% identity to bvu:BVU_2249)

Predicted SEED Role

"DNA polymerase III subunits gamma and tau (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9J6C8 at UniProt or InterPro

Protein Sequence (603 amino acids)

>HMPREF1058_RS15350 DNA polymerase III subunit gamma/tau (Phocaeicola vulgatus CL09T03C04)
MENYIVSARKYRPATFESVVGQHALTITLKNAIATGKLAHAYLFCGPRGVGKTTCARIFA
KTINCQTPTAEGEACNQCESCLAFNEQRSYNIHELDAASNNSVEDIRSLIEQVRIPPQIG
KYKVYIIDEVHMLSQAAFNAFLKTLEEPPHHAIFILATTEKHKILPTILSRCQIYDFNRI
GIKDTIDHLQYVAKLEHINAEPEALTVIAQKADGGMRDALSIFDQVVSFTGGNITYKSVI
ENLNVLDYEYYFKLTDLLLENKVPESMLLFNDVLKKGFDGSHFITGLSSHFRDLLVSKDP
STLQLLEVGAGIRDRYKEQAQKCDQKFLYRAMKLCNDCDLNYRASKNKRLLVELTLIQCA
QLTLPDADDVSGGRGPKKILKPLFTQQAASTAATQSQPQAKTAAAQTAATAAPQPQGTST
AGSMNASRPSPLPQTREEKKIPVFKAGSLGISLRRPLHEQQAAEKQEAKAASTAAQNDAT
YEDYIFNEKDLDYYWREFAAALPKEEKANSARMMNMHPHLLNDTTFEVTVDNDMVEKYMV
QLIPSVQNHLRERLHNRKITMTVRVSAPTENIRAYSHVERFQMMSKKNPNLLKLKEALGL
ELS