Protein Info for HMPREF1058_RS15195 in Phocaeicola vulgatus CL09T03C04

Annotation: family 43 glycosylhydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 333 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF04616: Glyco_hydro_43" amino acids 35 to 317 (283 residues), 241.3 bits, see alignment E=7.3e-76

Best Hits

KEGG orthology group: K06113, arabinan endo-1,5-alpha-L-arabinosidase [EC: 3.2.1.99] (inferred from 99% identity to bvu:BVU_2231)

Predicted SEED Role

"Arabinan endo-1,5-alpha-L-arabinosidase (EC 3.2.1.99)" in subsystem L-Arabinose utilization (EC 3.2.1.99)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.99

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9A3Y9 at UniProt or InterPro

Protein Sequence (333 amino acids)

>HMPREF1058_RS15195 family 43 glycosylhydrolase (Phocaeicola vulgatus CL09T03C04)
MRKNLILSICFCLVSCSSSSAQEEIPDGDKTSYYWNPVIDYSLPDPTIIEGGDGYYYLYA
TEDIRNLPIHRSKDLINWEWVGTAFTDRTRPDFEPGGGLWAPDINKIGDTYVLYYSMSKW
GGEWTCGIGCATADKLSGPFKDHGLMFRSNEINVQNSIDPFYIEDAGKKFLFWGSFRGIY
GIELSEDGLSIKQGKKPRQVAGTAYEGTYIHKKEGFYYFFASIGTCCEGLNSTYTTVVAR
SENLFGPYVDKNGRTMMDNQHEVLIHKNSSFVGTGHNSEIVTDKVGNDWVFYHAVVTKHP
EGRVLMMDKISWKDGWPVVATDSPSLKSEKPVL