Protein Info for HMPREF1058_RS15160 in Phocaeicola vulgatus CL09T03C04

Annotation: beta-galactosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 604 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF02837: Glyco_hydro_2_N" amino acids 102 to 180 (79 residues), 57.1 bits, see alignment E=3.5e-19 PF00703: Glyco_hydro_2" amino acids 214 to 308 (95 residues), 40.2 bits, see alignment E=7.9e-14 PF02836: Glyco_hydro_2_C" amino acids 351 to 477 (127 residues), 24.3 bits, see alignment E=2.4e-09

Best Hits

KEGG orthology group: None (inferred from 100% identity to bvu:BVU_2224)

Predicted SEED Role

"Beta-galactosidase (EC 3.2.1.23)" in subsystem Galactosylceramide and Sulfatide metabolism or Lactose and Galactose Uptake and Utilization or Lactose utilization (EC 3.2.1.23)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.23

Use Curated BLAST to search for 3.2.1.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9J6F8 at UniProt or InterPro

Protein Sequence (604 amino acids)

>HMPREF1058_RS15160 beta-galactosidase (Phocaeicola vulgatus CL09T03C04)
MKNFLILSLLLAFLTTEVCAQWKPAGDKIKTQWANKINTSAVLPEYPRPIMERNEWKNLN
GLWEYAITDLGGNVPAHFDGQILVPFAVESSLSGVGQRVGAKKELWYSRSFEVPVAWKNK
NVLLHFGAVDWKADIWVNDVKVGSHTGGFTPFSFDITAALSGKGNNKLVVKVWDPTDEGY
QPRGKQVNNPEGIWYTPVTGIWQTVWLEPVTARHIEELRITPDIDQHLLTVKAHLNMRAP
SDLIEVNVYDGNQLVATGKSINDEAVVIPMPEDAKLWSPDFPFLYTLKVMLKSDNKILDQ
VNSYAAMRKYSTKRDANGIVRLELNNQPLFQFGPLDQGWWPDGLYTAPTDEALVYDIQKT
KDLGFNMIRKHIKVEPARWYTHCDQLGIIVWQDMPSGDRNPEWQNRKYFEGTEKKRSAVS
EACYRKEWKEIMDCLYSYPCIGTWVPFNEAWGQFKTPEIAEWTKEYDPTRLVNPASGGNH
YTCGDMLDLHNYPAPEMYLYDAQRANVLGEYGGIGWVVKNHIWEPDRNWGYIQFNSSKEV
TDEYIKYTDMLYDLITRGFSAAVYTQTTDVEVEVNGLMTYDRKVIKVDEKRVREANARIC
KSLK