Protein Info for HMPREF1058_RS15080 in Phocaeicola vulgatus CL09T03C04

Annotation: glycoside hydrolase family 97 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 642 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF14508: GH97_N" amino acids 23 to 278 (256 residues), 183 bits, see alignment E=9.6e-58 PF10566: Glyco_hydro_97" amino acids 284 to 545 (262 residues), 350.9 bits, see alignment E=8.1e-109 PF14509: GH97_C" amino acids 547 to 642 (96 residues), 98.7 bits, see alignment E=2.8e-32

Best Hits

KEGG orthology group: None (inferred from 46% identity to cpi:Cpin_5410)

Predicted SEED Role

"Alpha-glucosidase (EC 3.2.1.20)" in subsystem D-Galacturonate and D-Glucuronate Utilization or Maltose and Maltodextrin Utilization (EC 3.2.1.20)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.20

Use Curated BLAST to search for 3.2.1.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9A2W9 at UniProt or InterPro

Protein Sequence (642 amino acids)

>HMPREF1058_RS15080 glycoside hydrolase family 97 protein (Phocaeicola vulgatus CL09T03C04)
MKKTLLCLMMAWGSLAFAENYTVDSPDSRITVNVETGTNTTYSVTFNGKMILNPSPISMT
FDNGTVIGRNMEVKNVERSTQNQVLKPVVRQKSKQIIDHYNEMVLDAENYKLYFRVYNDG
LAYRFHTDFPDSLKVLNEEVIYCFPEDYNTLFPEERSMLSAQQPLFKPMKLSEIGTDRFC
STPILIKVDENARIFISESDLESYPGMFLRKQGKNELAGKFAAVSLEDYKTDDRQIFPTK
RADYIARVNGTRNYPWRAMIVAENDANLITNQLIYKLAPEAEGDYSWVRPGKIAWDWYNA
LILTGVDFKCGINNDTYKYYIDFASKYGIEYVVIDDGWSEAWDVTKTIPEINMEELVAYG
KKKNVDLILWVSWAPFREKIDEAFDKFSQWGIKGIKMDFMNRDDQEMVDFYYEVARKAAA
RKMLVDFHGAYKPTGWLRTFPNVLTSEGVAGLENHKWGSFVTPKHNVTLPFTRMVAGPMD
YTPGAMINFHEKDHKIWFNLPASVGTRCHQLGMYVVYESPLQMLADSPSNYYREPVCMEF
LSQVPVVWDETRVLKASVGEYVVVARRHGDTWYIGGMVGEKGQKFEIDLDFIKGNKTLTY
WEDGVNVDMNANDFARRVQKVKQGDKITITMYDGGGYAAIIK