Protein Info for HMPREF1058_RS14415 in Phocaeicola vulgatus CL09T03C04

Annotation: sodium ion-translocating decarboxylase subunit beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 411 transmembrane" amino acids 17 to 38 (22 residues), see Phobius details amino acids 45 to 62 (18 residues), see Phobius details amino acids 101 to 123 (23 residues), see Phobius details amino acids 135 to 158 (24 residues), see Phobius details amino acids 192 to 215 (24 residues), see Phobius details amino acids 245 to 271 (27 residues), see Phobius details amino acids 292 to 310 (19 residues), see Phobius details amino acids 315 to 315 (1 residues), see Phobius details amino acids 317 to 342 (26 residues), see Phobius details amino acids 353 to 372 (20 residues), see Phobius details amino acids 384 to 410 (27 residues), see Phobius details PF03977: OAD_beta" amino acids 24 to 410 (387 residues), 459.5 bits, see alignment E=3.8e-142 TIGR01109: sodium ion-translocating decarboxylase, beta subunit" amino acids 24 to 405 (382 residues), 412.2 bits, see alignment E=9e-128

Best Hits

KEGG orthology group: K01572, oxaloacetate decarboxylase, beta subunit [EC: 4.1.1.3] (inferred from 100% identity to bvu:BVU_1976)

Predicted SEED Role

"Oxaloacetate decarboxylase beta chain (EC 4.1.1.3)" in subsystem Na+ translocating decarboxylases and related biotin-dependent enzymes or Pyruvate metabolism I: anaplerotic reactions, PEP (EC 4.1.1.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.1.1.3

Use Curated BLAST to search for 4.1.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9UG03 at UniProt or InterPro

Protein Sequence (411 amino acids)

>HMPREF1058_RS14415 sodium ion-translocating decarboxylase subunit beta (Phocaeicola vulgatus CL09T03C04)
MEDIFERLYDMTAFSNIIAEPQFLIMYAIAFILLYLGIKKKYEPLLLIPIAFGVLLANFP
GGEMGVVQADENGMVMVNGALKNIWEMPLHEIAHDLGLMNFIYYMLIKTGFLPPIIFMGV
GALTDFGPMLRNLRLSIFGAAAQLGIFTVLLVAILMGFTPKEAASLGIIGGADGPTAIFT
TIKLAPHLLGPIAIAAYSYMALVPVIIPLVVKIWCTKKELSINMKEQEKKYPSSVEIKNL
RVLKIVFPIVVTTVVALFVPSAVPLIGMLMFGNLIKEIGSDTSRLFDAASNSIMNAATIF
LGLSVGATMTTEAFLNWTTIGIVIGGFLAFALSISGGILFVKLVNLFTKKKINPLIGATG
LSAVPMASRVANEIALKYDPKNHVLQYCMASNISGVIGSAVAAGVLISFLQ