Protein Info for HMPREF1058_RS13815 in Phocaeicola vulgatus CL09T03C04

Annotation: amino acid permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 552 transmembrane" amino acids 30 to 55 (26 residues), see Phobius details amino acids 61 to 84 (24 residues), see Phobius details amino acids 96 to 124 (29 residues), see Phobius details amino acids 155 to 173 (19 residues), see Phobius details amino acids 184 to 205 (22 residues), see Phobius details amino acids 225 to 249 (25 residues), see Phobius details amino acids 262 to 282 (21 residues), see Phobius details amino acids 326 to 345 (20 residues), see Phobius details amino acids 376 to 395 (20 residues), see Phobius details amino acids 401 to 419 (19 residues), see Phobius details amino acids 431 to 451 (21 residues), see Phobius details amino acids 457 to 476 (20 residues), see Phobius details amino acids 491 to 511 (21 residues), see Phobius details amino acids 523 to 544 (22 residues), see Phobius details PF13520: AA_permease_2" amino acids 28 to 453 (426 residues), 181.7 bits, see alignment E=3.7e-57 PF00324: AA_permease" amino acids 36 to 451 (416 residues), 121.5 bits, see alignment E=6.1e-39 PF13906: AA_permease_C" amino acids 429 to 479 (51 residues), 58.4 bits, see alignment 9.3e-20

Best Hits

KEGG orthology group: K03294, basic amino acid/polyamine antiporter, APA family (inferred from 100% identity to bvu:BVU_1861)

Predicted SEED Role

"Amino acid permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9J536 at UniProt or InterPro

Protein Sequence (552 amino acids)

>HMPREF1058_RS13815 amino acid permease (Phocaeicola vulgatus CL09T03C04)
MGLFIKKPFAALQAEANESGNKTLKRVLGPWSLIALGVGVIIGAGLFSITGTVAAGYTGP
AITLSFAIAAIGCCFAGLCYAEFASMIPVAGSAYTYSYATMGELIAWIIGWDLVLEYTVA
ATTVSISWSRYLVVFLEGVGINIPHALAACPWDGGIVNIPAALIVVLMSIFLIRGTEGSS
IFNGFIVFLKVAVILIFVVLGWKYINAENYVPYIPANTGTLGEFGFSGVLRGAAIVFFAF
LGFDAVSTAAQETKNPKRDMPIGILGSLLICTILYMVFAYVMTGVAHYSDFAGQQGIAPV
AVAIDHMGHADATGVIHPDYPWLNRAIVLAILFGYCSVIMVTLLGQSRVFLSMSRDGLLP
PFFSKIHEKYRTPAHSNLLFMVIVGGLAAFVPARVAGEMTSIGTLFAFTLVCAAVLIVRK
SMPDVHRAFKTPFVPTVPILGILTCLCMMLFLPADTWIRLVLWMLIGLDVYACYGVKHSK
LEHNVKRRKGLTILNMTGIALSVLSVITGLWHQQTVGWEEDKTLLAISFVFAFTHCAFYM
VRIWKQTSEKKK