Protein Info for HMPREF1058_RS13560 in Phocaeicola vulgatus CL09T03C04

Annotation: beta-glycosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1122 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF02837: Glyco_hydro_2_N" amino acids 92 to 183 (92 residues), 40.1 bits, see alignment E=7.7e-14 PF00703: Glyco_hydro_2" amino acids 213 to 321 (109 residues), 57.2 bits, see alignment E=5.6e-19 PF02836: Glyco_hydro_2_C" amino acids 331 to 479 (149 residues), 27 bits, see alignment E=5.1e-10 PF07691: PA14" amino acids 838 to 969 (132 residues), 29.5 bits, see alignment E=1.2e-10

Best Hits

KEGG orthology group: None (inferred from 98% identity to bvu:BVU_1809)

Predicted SEED Role

"Beta-galactosidase (EC 3.2.1.23)" in subsystem Galactosylceramide and Sulfatide metabolism or Lactose and Galactose Uptake and Utilization or Lactose utilization (EC 3.2.1.23)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.23

Use Curated BLAST to search for 3.2.1.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I8ZYT7 at UniProt or InterPro

Protein Sequence (1122 amino acids)

>HMPREF1058_RS13560 beta-glycosidase (Phocaeicola vulgatus CL09T03C04)
MKKSIVAIAFLLLCPFYGVRAQERPFFDLSGKGWHLWQDKNAAWQTEDIYLTLEEAQKSP
VIVPTAGWDILTSAQTLPVQVPGTAEEYLQTQSGPEGDITGVTWWSRTMDIPVLKKGQKV
FLNFGSIRSRAEIFINQRLVDYQIVDNVPFETDITPYIKSGEQVQLAVRITDAGGNHDWR
DSRTIPWGDKMLPPGHGFGGITGKVGMKVCNAVYVADIYMQNTPQITTANAILTLQNEKG
KTTKQDLRITVYEWQNKEKIVYSKEIKGVSLNKGLNELKIPVSAPDAKLWSVDDPNLYVC
EVELSEGKNWVDKDSRRFGFRWFEASGIGEDAVFRLNGKRIMLRSAISWSFWPVNGIFPS
EELAERQIRIAKELGLNMLNFHRFIGNTDVMNYADELGLLYFEEPGGFRLDVRQPFMNAV
LHEKVIRMVKRDRSHPCLVIYNMMNESGNAAPEKLELEIQAMKDMRVLDPSRLILRTSAW
AKGDDIEDQAKIHIRPYDEKVYWSGWYDYHRAGGPAVWNEGLYKGPDDYYNDTKNKREIV
FFGEEGALSSPPRLEKNKEDLEKYNYKGWDGREFLRWYDEFNKFLDAKQLRTVYPTVDDL
CVAMGTVSYEHQGRKIESARMNNLTDAYVVNGWESELTENYSGIVDCFRYPKSDPAIIAR
YNQPLYVAVKTRQQVAAAGGKVTVDFYLINEKNVRGNHQLKISVTDYQGKVMEVGTYETE
AAGGEVYGQLLVKDVKIPVPAVGGLCRIEAKLCKENSVVTTGYDDILSVNLASNMLDGKG
AVWEDGSALQNFLKGKTKEAVAAYEDNLGKLDWIMVARPPRKDQLTMVPMEALRSADGKP
GLDVVYYEDMEFQKEVYHEVAKVVNLSAIEGATPSSFVYMLDGYGIKWSGKVLPSVSGEY
TIIPQSNDRSMIEVFVNGKKIYEITRKKEHLGDGKVYLEGGKSADIEIRFRHPRSNARCR
LDWAVPNDKMPDAQRLMERAVNDGTKIFIIQSADEWSEFIAANSKVVFKDKFFVGTNWLG
GVMFNKPHDIFKELPVGNALNWPYQALIHTGVERMGLVMEGEELLVGAYHTYPMAIGTAM
GIVPMGKGSVLFSTLDIYGNIINDSAAGLVAKKLIFNMIDFK