Protein Info for HMPREF1058_RS13450 in Phocaeicola vulgatus CL09T03C04

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1063 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 37 to 1063 (1027 residues), 842.3 bits, see alignment E=7e-257 PF13620: CarboxypepD_reg" amino acids 38 to 97 (60 residues), 45.4 bits, see alignment 1.7e-15 PF13715: CarbopepD_reg_2" amino acids 39 to 120 (82 residues), 72.1 bits, see alignment 6.1e-24 PF07715: Plug" amino acids 128 to 236 (109 residues), 71.2 bits, see alignment E=2e-23 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 212 to 242 (31 residues), 65.6 bits, see alignment (E = 2.5e-22) PF00593: TonB_dep_Rec" amino acids 440 to 917 (478 residues), 62.9 bits, see alignment E=1.1e-20

Best Hits

KEGG orthology group: None (inferred from 55% identity to pru:PRU_1591)

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9A003 at UniProt or InterPro

Protein Sequence (1063 amino acids)

>HMPREF1058_RS13450 TonB-dependent receptor (Phocaeicola vulgatus CL09T03C04)
MKNNKMLGGTINKVPVKMVFLLAIFLVVAVTGFAQSRTVSGTVIDKTGEAVIGASVVVRG
TTNGTITDFDGNFTLQNVPVNGTIQVSFVGYKTVDIPIQNQSIIKVTLEEDTETLDEVVV
VGYGVQKKSDVTGAMSSVGAEELTSRPVNNAFEALQGKAAGVDITTSERPGKLGDIRIRG
NRSLSASNSPLYVVDGVPLLSASAIETLNPRDIEAIDVLKDASATAIYGSRGANGVVLVT
TKQGKAGQFSLNYSGTLTISNLVDKSPAMSAADFIEFRRWAAYNLDPATYADPRNPTYES
DKLLFDSALDGQTSRDNVLKGWVNGTWDPSLVTNTDWTDYVTQTSISHEHTVSASGGTEQ
INAYGSFGYLSNKGTQKGQWYDRYTAKISVNIKPVKWFTLNASMNATWSEQDYGMSTLGG
SSSHVADAIYGAAKGIYRMAVPYDADGKLIINPGGESGMYNIIGEWNKSTQLSQTMRTLA
NFSATLGLGEIWKPLEGLSYKINFGPDYRNWREGSYVDGSSIRRINADSSEGLNYARLKN
RRDFSWTLDNMITFDRTFAEKHKVGVTLLQTVSAWNIETSEMSAQNIANRDFLWNAFNTV
DIQNPDNKAAMGSGLTERQLASYMVRLNYGFNERYLLTVSGRWDGASQLAPGHKWDFFPS
AALAWRVNQEDFLKDIVWLDNLKFRVGFGTTGNSSVDPYATKGDITGVYLPFNGMSNQIG
YVTNEPYYIKDGKPMANEELGWEKTTQVNFGLDFGVLNNRISASIDAYFSRTNDLLMRTN
IPTLTGYPNTYANIGKTKNHGVEIALNAVPVQTRSGFTWETSLNAAYQKDEIVELAYGKN
DMVSNSWFIGESIGVYYGYQNDGLWQDTPEDHAEMEKWNANGYHFTPGNVKPKDQDGDYK
MGDNDRVVLGNKNPRWTMGWTNNFSWKGIELGITLNGRMGYMVDGKEEALTAHTNQREVD
YWTPDNPNAEFQKPILAQATSGSLDDFSGTLGYRNAAFLKIRNISLGYNFPKNKITKLGI
SHLKVYGQAVNPGSLYQSIEGYDLDTGSTNFNRSFVFGLELGF