Protein Info for HMPREF1058_RS13410 in Phocaeicola vulgatus CL09T03C04

Annotation: SusC/RagA family TonB-linked outer membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1143 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 126 to 1143 (1018 residues), 994.7 bits, see alignment E=6.4e-303 PF13715: CarbopepD_reg_2" amino acids 127 to 207 (81 residues), 65.7 bits, see alignment 7.6e-22 PF13620: CarboxypepD_reg" amino acids 127 to 195 (69 residues), 44.5 bits, see alignment 4.1e-15 PF07715: Plug" amino acids 215 to 320 (106 residues), 69.8 bits, see alignment E=6.6e-23 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 296 to 326 (31 residues), 60.7 bits, see alignment (E = 8.5e-21) PF00593: TonB_dep_Rec" amino acids 556 to 1102 (547 residues), 58.4 bits, see alignment E=3.2e-19

Best Hits

KEGG orthology group: None (inferred from 100% identity to bvu:BVU_1773)

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I8ZYW7 at UniProt or InterPro

Protein Sequence (1143 amino acids)

>HMPREF1058_RS13410 SusC/RagA family TonB-linked outer membrane protein (Phocaeicola vulgatus CL09T03C04)
MIKSCRLILNKTPLPMKLSVLFLICSLSMTYAAESYAQKTMISLEVRNETVGTVLEKLKK
ESGFDFFFNNKHVDLKRIVSVSANNNNIFKILDQIFAGTNVKYSVLEKKIILSTEIVQGI
QQEQNKVTGIVKDANGEPIIGANVIVKGQSTGTITDIDGRFVLDTPKDAVLQITYIGYVS
QEVKVSGKKELNVVLKEDTETLEEVVVVGYGVQKKANLTGAVSSVKMDEILGDRPVTSVS
NVLMGAMPGLQVTGTSGQPGAEMSFNIRGVNSINEGAPLVLVDNVEMDINMLDPNDIESI
SVLKDAASSAIYGARAAFGVILVTTKKGMKDTRFSINYSNNFSFSKPSNLPHKATPLQTV
QAYKDMGTVSYQTGQNVDTWLELLKEYNTNSSNYPDGYAVVDGLRYSLQETDLLNDMMET
GFQQTHNISVGGGNKSISYRMSAGMVNQNGILVTDKDSYKRYNISSYIRSDIHSWITPEL
DIKYANSHSELPYTSASYGIWGAAVAFPSYFPLGNMELDGEILPINTPHNFINLSAPKEN
DRNDLRIFGKLTITPFKDLKIIGEYTFNRKTREITTFDKKFAYAHGANFRKEQSVSNSKY
EIENRATNYNAFNVYANYNKTLGQHDIGIMAGFNQESNSYKMMKASRTDMINEDLPSLSQ
ATGDYKNSDEFEEYHVRGLFYRINYSYAGKYLLETNGRYDGSSKFPKENRFGFFPSVSVG
WRVSEEQFMEWSKVFLSNLKLRGSYGNIGNQSIEPYAFIPGMDSPLANWVVNGQATTTLV
PPALVSNSFTWEKVSTLDFGFDLGLFNNRLNVVFDWYQRDTKGMLAPGMELPGVLGAKAP
LQNSADLRAKGWEISLDWNDRIGNVQYYLGFNLYDSRTKITKYDNEVGLLGKDSDDNLIY
RKGMELGEIWGYTTDRLYTTEDFDSQGKLKNNIPKVEGYNPNPGDILYVDFDGNGIINNG
KNTSNEPGDTRIIGNDTRRYQYGIRGGATWKGISLSFILQGVGKRDLWLMNELFYPHYDA
YSTLFDSQLNYWTPEHTNSYFPRLYEKAEGNTKANQKPQTRFLQNGAYLSIRNISLSYTF
PIKLIKPLGITNLSVFFSGENLFTFDHLPKGIDAERVVTDNLGQRGFTYPYMRQFSFGIN
LSL