Protein Info for HMPREF1058_RS13175 in Phocaeicola vulgatus CL09T03C04

Annotation: SusC/RagA family TonB-linked outer membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 922 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 36 to 922 (887 residues), 549.6 bits, see alignment E=1.9e-168 PF07715: Plug" amino acids 47 to 144 (98 residues), 31.5 bits, see alignment E=1.1e-11 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 120 to 150 (31 residues), 59.3 bits, see alignment (E = 2.4e-20)

Best Hits

KEGG orthology group: None (inferred from 56% identity to bth:BT_2820)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I8ZZ33 at UniProt or InterPro

Protein Sequence (922 amino acids)

>HMPREF1058_RS13175 SusC/RagA family TonB-linked outer membrane protein (Phocaeicola vulgatus CL09T03C04)
MKKLYILVLISALPVWGIAQSEQNDSNKISSWETTKIGYELSYSKDVTGFSTILKGSDIF
ENATSIDVSKALYGKIAGLNVYQGLGSSSDNISGLSIHGHAPIVLIDGYVRSIQDVNAAE
IESISVLKDATATALYGVQGANGVVLLTTKRGTAGRLKATAKYQFGLSSQFRSPKFADAY
TYASYLNSALISDGFAPKYNTNELAAFKDETYPFAYPNVNWWDEVYKKIGTNHRLELTFD
GGSEKFRYFSVIDYMRDKGLFDNTSEDNRYNSNFTDTRLKVRANIDVAITNTTQFKFGLA
SGLREYNAPCFGNIYDVLYKIPSAAFPIRQENGIYGGNAIYGVNNPLALLNSTGSERKTY
GDLFVDANLCQDLGGLLKGLSADLSIAFDNCGGMFDKSTLTYRYSDLQPSIIDHTLVTNP
VIYGDDSEILNHSSGFHSLYMNATFRGKINYNYNRGLNQVNTSLIYDQNSFTANGRNQSK
KRQSIMAVASYSYNSRYSISGVLNYSGSAYLDPDDRFDLYPAVSAAWNMTDEGFMKNLKF
INNLRLNVSYGLSGWDGNLRHELFRQSYGNTDRSYYFTNNVAEVWGKGEGALPILNLSAE
RSAKGTLGFNLIAFNNHLSVDVEGFFEKRTQILTNANNVSGIIGIGIGQLCSGIEKYRGF
DASFSWKDRISAVDYGLDVNMSYVNSELVEANEEYQQYDYLYHKGNRVGQSYGLEVEGFF
NSEMEINNSPQQLFGGNIRPGDIKYKDQNGDNVIDSQDRVKMFGSSIPRFYFGFTLNVGY
KNFNLSADFQGLTGRTISLLDSPLYKPLVSNGNLSQTLLDNEQPWTVENATTATLPRLTT
LPNENNYQHNSLWFRDGSFLKLRNLRISYLYPKTKNHMADVKVYLQGNNLFSLDNVDGFD
PEQLGATYPSLRTYWMGLQFSF