Protein Info for HMPREF1058_RS11770 in Phocaeicola vulgatus CL09T03C04

Annotation: sulfatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 526 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00884: Sulfatase" amino acids 39 to 414 (376 residues), 188.2 bits, see alignment E=3.3e-59 PF01663: Phosphodiest" amino acids 49 to 361 (313 residues), 38.9 bits, see alignment E=1.2e-13 PF16347: SGSH_C" amino acids 364 to 514 (151 residues), 248.7 bits, see alignment E=3.9e-78

Best Hits

KEGG orthology group: None (inferred from 100% identity to bvu:BVU_1266)

Predicted SEED Role

"Mucin-desulfating sulfatase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I8ZWR7 at UniProt or InterPro

Protein Sequence (526 amino acids)

>HMPREF1058_RS11770 sulfatase (Phocaeicola vulgatus CL09T03C04)
MNRITSSVLYSLTGAAMLSSLPSCKVKKESDGNEKKSMNIVYIMCDDHSFQTISAYDQRY
MQTPNIDRIANEGIRFTNSFVANSLSGPSRACMLTGKHSHANGFTDNTTTFDGNQQTFPK
LLQANGYQTAMIGKWHLVSEPTGFNYWDILIGQGDYYNPKFIKNGERVQREGYATNIVTD
LAINWMDSIRDKSKPFCLFIHHKAPHRTWMPDLCDLDLYDDVTYPMPENFYDKYEGRIPA
SKQEMSIIKDMDLVYDLKMADKENEIHTTTGLEEAGRNMYNALNPEQKAVWDKHYDPIIA
KFKQDKLTGKALAEWKYQQYMHDYMRVIHSIDRNVGRVLKYLEENGLMENTMIVYTSDQG
FYMGEHGWFDKRFMYEESFRTPLLVRLPGGKKGDVDEMVQNIDYGPTILDLAGVEVPADM
HGVSFLPLLKGEKVPDWRKSLYYHFYEYPAEHAVRRHYGVRTERYKLMHFYNDIDCWELY
DLQEDPMEMHNIYGQPGTEELVKELKTELLRLQVQYDDPIRNIYKD