Protein Info for HMPREF1058_RS10960 in Phocaeicola vulgatus CL09T03C04

Annotation: NAD(P)-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 348 PF04321: RmlD_sub_bind" amino acids 16 to 264 (249 residues), 49.4 bits, see alignment E=1.1e-16 PF01370: Epimerase" amino acids 17 to 243 (227 residues), 105.6 bits, see alignment E=8.7e-34 PF01073: 3Beta_HSD" amino acids 18 to 265 (248 residues), 61.8 bits, see alignment E=1.7e-20 PF16363: GDP_Man_Dehyd" amino acids 18 to 337 (320 residues), 75.6 bits, see alignment E=1.6e-24 PF13460: NAD_binding_10" amino acids 21 to 201 (181 residues), 38.5 bits, see alignment E=3.5e-13 PF07993: NAD_binding_4" amino acids 80 to 191 (112 residues), 24.8 bits, see alignment E=3.5e-09

Best Hits

KEGG orthology group: None (inferred from 100% identity to bvu:BVU_1089)

Predicted SEED Role

"NAD-dependent epimerase/dehydratase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9UBD1 at UniProt or InterPro

Protein Sequence (348 amino acids)

>HMPREF1058_RS10960 NAD(P)-dependent oxidoreductase (Phocaeicola vulgatus CL09T03C04)
MNNEEFAQKNTCCLKKVLVTGASGFIGSFLVEGGLEREMQVWAGVRKSSSRTYLKDPRIQ
FAELDFAHPGRLTEQLAVHKQLHGGWDYIIHCAGVTKCRHKDEFDKGNYVYTRNFVEALR
TLDMVPRQFVYISSLSIFGPIHEDNYAPISERDTAMPNTAYGVSKLKSEHYLQSLNDFPT
VIFRPTGVYGPRERDYFLMAKSIKQHIDFAPGFKRQDLTFIYVRDLVQAVYLAIEHGVRQ
RAYFVSDGNVYSSRTFSDLIQKELGNPWVIHIKCPLFILKVVSLLAEFSARCLGKVSTLN
ADKYKIMKQRNWQCDISPLVEELGYRPEYPLDKGVKEIIAWYKKEGWL