Protein Info for HMPREF1058_RS10880 in Phocaeicola vulgatus CL09T03C04

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 612 transmembrane" amino acids 20 to 48 (29 residues), see Phobius details amino acids 76 to 117 (42 residues), see Phobius details amino acids 174 to 191 (18 residues), see Phobius details amino acids 197 to 213 (17 residues), see Phobius details amino acids 285 to 303 (19 residues), see Phobius details amino acids 309 to 326 (18 residues), see Phobius details PF00664: ABC_membrane" amino acids 77 to 323 (247 residues), 131.3 bits, see alignment E=5.7e-42 PF00005: ABC_tran" amino acids 391 to 540 (150 residues), 105.5 bits, see alignment E=3.7e-34

Best Hits

KEGG orthology group: K11085, ATP-binding cassette, subfamily B, bacterial MsbA [EC: 3.6.3.-] (inferred from 100% identity to bvu:BVU_1072)

Predicted SEED Role

"ABC transporter, ATP-binding protein"

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9UCB9 at UniProt or InterPro

Protein Sequence (612 amino acids)

>HMPREF1058_RS10880 ABC transporter ATP-binding protein (Phocaeicola vulgatus CL09T03C04)
MLKQFFSLLKRYILPYRKYLTWALILNFLSQWLNVFSFMAIVPILNILFKIDTKSYEYIP
MDIHNLDKDVLINNAYYFVSNFVATNGAFYTLAMMGGILIFMTMLKTAGYFASAAVMVPL
RTGIVRDIRIQVYNKVLSLPLSFFSEERKGDIIARMSADVTVVENSLTSSIDMLIRNPIA
LLVCFVTLFSVSWQMTLFVIFILPLTGWIMGVVSRKLKRQSSTAQAQWGDIMSQLDETLG
GLRVIKAFIAESKMSARFSKTNNDFRDAMNEMIIRQSSAHPMSEFLGTCVIVTVLLFGGA
LILNTNYAPMDAATFIFYLIILYSIINPLKEFSRAFYNIPQGLASMERIDMILKAENHIV
EPEQPLPLDAFTDKLEFKNVSFSYVEGRPVLNHINLTVPKGKTIALVGQSGSGKSTLVDL
VPRYHDVSEGALLIDGKNVKDVSIHSLRSLIGNVNQEAILFNDTFYNNITFGVENATMEQ
VIEAAKIANAHDFIMETEKGYDTMIGDRGGRLSGGQRQRVSIARAILKNPPILILDEATS
ALDTESERLVQEALERLMKSRTTIAIAHRLSTIKNADEICVLYEGDIVERGTHDELIALN
GYYKKLNDMQSL