Protein Info for HMPREF1058_RS10740 in Phocaeicola vulgatus CL09T03C04

Annotation: RagB/SusD family nutrient uptake outer membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 637 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF14322: SusD-like_3" amino acids 22 to 219 (198 residues), 58.8 bits, see alignment E=9.2e-20 PF07980: SusD_RagB" amino acids 294 to 627 (334 residues), 119.5 bits, see alignment E=2.4e-38

Best Hits

Predicted SEED Role

"Putative outer membrane protein, probably involved in nutrient binding"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9J0I8 at UniProt or InterPro

Protein Sequence (637 amino acids)

>HMPREF1058_RS10740 RagB/SusD family nutrient uptake outer membrane protein (Phocaeicola vulgatus CL09T03C04)
MKLKYIILPIIATSFAISSCNDFLDREPLTDNVNEGFFTEPSQLQAYCNKKYELLPDFKD
TNLFTNDQTSDNQAGTDPVDFFLPQRIKVAATGSYNRQGHLRDCNRLLYYALENIQKGEL
EDTRETQQYIGEIYFFRAYIYFEYLRKFGDFPIIKSELSADDYAANVEANKRKPRNEVAR
FILEDLNEAIARLLPRSNNLTNHRLNRECAYLFKSRVALYEASWETYHQGTARVPGGPGW
PGGTFNGNLNTEIDFFLTEAMASAKEVAEAIQISDKIEDYMNMFNQYDLSSNKEVLLWRM
YSADAKVNSLVEGNYHSIYNENGEGCVGQGGGYTRSMVETFLTTNGLPIYAPENTEYKGD
KSIPDVMENRDLRLVESTFKPGDMVWRGGNMDQDGRMVYANLLQAYQNLSRTATGYLVRK
GWRDSNVAPADNSPLAYMIFRASEAYLNYMEADYMKNKNLDDYSKKYWRALRKRAGVSEN
FQKTIDATDLSKENDLAVWSGSQMIDKTLYNIRRERRCEFIAEGMRKDDLLRWRSLDKMK
NYQTEGFNWQEYQKEPYYVKQLAAGLVVSNSKYLRPHFANELIITNNGYNFEEANYLTPI
SYDVFRLSTPEKGGDISTSVVYQNPGWPVGANQYALQ