Protein Info for HMPREF1058_RS09535 in Phocaeicola vulgatus CL09T03C04

Annotation: alkyl hydroperoxide reductase subunit F

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 516 TIGR03140: alkyl hydroperoxide reductase subunit F" amino acids 1 to 512 (512 residues), 748.8 bits, see alignment E=1.4e-229 PF13192: Thioredoxin_3" amino acids 124 to 194 (71 residues), 31.4 bits, see alignment E=8.3e-11 PF07992: Pyr_redox_2" amino acids 211 to 499 (289 residues), 176.2 bits, see alignment E=5.2e-55 PF13738: Pyr_redox_3" amino acids 258 to 482 (225 residues), 71.2 bits, see alignment E=4.7e-23 PF00070: Pyr_redox" amino acids 353 to 421 (69 residues), 51.6 bits, see alignment E=5.6e-17

Best Hits

Swiss-Prot: 47% identical to AHPF_XANCH: Alkyl hydroperoxide reductase subunit F (ahpF) from Xanthomonas campestris pv. phaseoli

KEGG orthology group: K03387, alkyl hydroperoxide reductase subunit F [EC: 1.6.4.-] (inferred from 99% identity to bvu:BVU_0846)

Predicted SEED Role

"Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)" in subsystem Thioredoxin-disulfide reductase (EC 1.6.4.-)

Isozymes

Compare fitness of predicted isozymes for: 1.6.4.-

Use Curated BLAST to search for 1.6.4.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9U8H5 at UniProt or InterPro

Protein Sequence (516 amino acids)

>HMPREF1058_RS09535 alkyl hydroperoxide reductase subunit F (Phocaeicola vulgatus CL09T03C04)
MLDSAIKDQLKGLFAQLEAHYTFDIFVHPQHESRAELVDSLEEVASCSDKLSCRLQDSEG
LKFILLKEGKDTGITFRAVLGGHEFTSLLMAVLNADGKGKNFPDEFITRRIKALQGPISL
TTYLSLTCTNCPDVVQALNMMVLLNGQIRHEAVDGSINEEEVERMKVQAVPTVFADGEQI
HVGRSSMGDLLEKLEARYGSVELEAVETKEYDVLVAGAGPAGATAAIYSARKGLKVAIIA
ERIGGQVNETMGIENLISVPQTTGKQLAQDLKKHLAEYHIDILENRRIEKVEVAEGMKVL
SVKGGETYKAPVLIIATGANWRKLNVPGEEKYIGHGVAFCPHCDGPFYKDKEVAVIGGGN
SGVEAAIDLAGVCSKVTVFEFMDTLKADTVLQEKAKSLPNVDIITNTQTVEVLGNGDKVV
GLIKKDRSSEKEEIFALDGIFVQIGLTANSTLFKELLETNRMGEILTDKNGRTSVKGIYA
AGDVTDVSYKQIVIAMGEGAKAALAAFEDRMRGTIY