Protein Info for HMPREF1058_RS09355 in Phocaeicola vulgatus CL09T03C04

Annotation: elongation factor G

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 705 TIGR00484: translation elongation factor G" amino acids 4 to 699 (696 residues), 1042.6 bits, see alignment E=0 PF00009: GTP_EFTU" amino acids 9 to 284 (276 residues), 203.3 bits, see alignment E=7e-64 TIGR00231: small GTP-binding protein domain" amino acids 9 to 182 (174 residues), 106.6 bits, see alignment E=1.1e-34 PF03144: GTP_EFTU_D2" amino acids 327 to 394 (68 residues), 68.4 bits, see alignment E=1.5e-22 PF14492: EFG_III" amino acids 407 to 480 (74 residues), 112.2 bits, see alignment E=2.4e-36 PF03764: EFG_IV" amino acids 482 to 603 (122 residues), 135.6 bits, see alignment E=1.9e-43 PF00679: EFG_C" amino acids 607 to 692 (86 residues), 96.1 bits, see alignment E=2.7e-31

Best Hits

Swiss-Prot: 100% identical to EFG_BACV8: Elongation factor G (fusA) from Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / NBRC 14291 / NCTC 11154)

KEGG orthology group: K02355, elongation factor G (inferred from 100% identity to bvu:BVU_0807)

Predicted SEED Role

"Translation elongation factor G" in subsystem Translation elongation factor G family or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9U9D8 at UniProt or InterPro

Protein Sequence (705 amino acids)

>HMPREF1058_RS09355 elongation factor G (Phocaeicola vulgatus CL09T03C04)
MAKHDLHLTRNIGIMAHIDAGKTTTSERILFYTGLTHKIGEVHDGAATMDWMEQEQERGI
TITSAATTTRWKYAGNTYKINLIDTPGHVDFTAEVERSLRVLDGAVAAYCAVGGVEPQSE
TVWRQADKYNVPRIGYVNKMDRSGADFFEVVRQMKDVLGANACPVVIPIGAEESFKGVVD
LIKMKAILWHDETMGADYSVEEIPANLVDEANEWREKMLEKVAEFDDALMEKFFDDPSTI
TEEEILRALRAGTLKMDIVPMFCGSSFKNKGVQTLLDYVCAFLPSPLDTPAIVGTNPTTG
AEEDRKPSEDEKTSALAFKIATDPYVGRLTFFRVYSGKVEAGSYIYNTRSGKKERVSRLF
QMHSNKQNPVEVIGAGDIGAGVGFKDIRTGDTLCDEDAPIVLESMEFPDPVIGIAVEPKT
QKDLDKLSNGLAKLAEEDPTFTVKTDEQSGQTIISGMGELHLDIIIDRLKREFKVECNQG
KPQVNYKEAITKTVELREVYKKQSGGRGKFADIIVAIGPVDEDFTQGGLQFIDEVKGGNV
PKEFIPSVQKGFQTAMKNGVLAGYPLDSLKVVLKDGSFHPVDSDQLSFEICAIQAYKNAC
AKAGPVLTEPIMKLEVVTPEENMGDVIGDLNKRRGQVEGMESSRSGARIVKAKVPLAEMF
GYVTALRTITSGRATSSMTYDHHAQVSSSIAKAVLEEVKGRVDLV