Protein Info for HMPREF1058_RS08170 in Phocaeicola vulgatus CL09T03C04

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1115 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 46 to 1115 (1070 residues), 863.7 bits, see alignment E=2.4e-263 PF13620: CarboxypepD_reg" amino acids 46 to 104 (59 residues), 45.5 bits, see alignment 1.2e-15 PF13715: CarbopepD_reg_2" amino acids 47 to 127 (81 residues), 76.9 bits, see alignment 1.5e-25 PF07715: Plug" amino acids 135 to 243 (109 residues), 72.2 bits, see alignment E=7.2e-24 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 220 to 249 (30 residues), 56.1 bits, see alignment (E = 2.3e-19)

Best Hits

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9U5Y1 at UniProt or InterPro

Protein Sequence (1115 amino acids)

>HMPREF1058_RS08170 TonB-dependent receptor (Phocaeicola vulgatus CL09T03C04)
MKNEFFKFSSRRILFSTVMASALLAGSPQTVFAEVNGVQTVMQTGTVKGQVVDANGEPII
GASVLVKGTTNGTITDFDGNFTLNNASKGILVVSYIGYKTQEVPVNEKNLMKIILKEDTE
VLDEVVVVGYGTQKKATLTGAVASVSGDILESRPVSNTAIGLQGQVPGLTITRTSARPGN
EDMAIQIRGASSTNKVEPLIIIDGVPAISNTEFSSLNPNDIESVSVLKDASAAIYGARAA
GGVVLVTTKKGKKGDKLKVSYNGMVTANTPANMLPLAGMRDWASAMAEASYQDYVESDGK
GGEVITQRYTNGQLWNNILVSGGKTPHAGVSFDDTNLLVLDKMAIGDPFTYVDANSQMHY
YESNNWLDLIYGTTWSTQHNVNVQGSSEKARWMASLGYANDRSVITATDDGAKKYNARLN
ADYDLTKWLTFNINMSYSNRYTDGPIDGLDGNNSGMYDAPIAAPYTPSGNYYDLYMIGRS
PLSAMQAGGRNQQEFETFRYSNTLTAQLTKDLKATGAMSFIKNNNIQTEYKTTYYVGAPY
VVGGTAETGYDIEEKLNAVNPGTSSYVQERSQRTFYENYSIQLDYNHTFGEVHNVAVMVG
ANAEKRTYKNVKAKRTELLYDGLHDLNTGSAEASHQTIEGGSNEQGYVSYLARLNYDYAG
KYMIEALGRRDGTSKFHPDYRWCNFGAASIGWRISEESFIKDNLKWLDNLKLRASFGITG
GAVSELGNYDYLSSIALGTTYFNTGLVQSAWLSKLTDYTRTWEKLENLNIGVDFALLGNR
LTGSFDWYQKKNNNMLVSLNYPDVLGTNPAATNDAKLRVRGWEVALGWNDRAGDVNYWVN
ASLADSRSMVLDYAGTDRWTAGLVKVREGYPLNSLFVYKTEGFFASYEEIEKYYEQYKGN
SALSGVAQTSTNTHLRPGDRKKILLLDPANDTTGGKGNTGAGDVYHYGDIDPHFTFGLNA
GAKWKNIDFSLFVQGVGQRYFLREGGLNTCAFYANYNNILTTQLDTWTWDNQNAEYARLS
LQGGKNKWNVDNNDASVQNAWYARLKNVTVGYTIPSTITDKWKIEKLRFYFSGDNIAEIT
GLSDGFDPEKGYTASNTRTSLPFSRSWTIGVDLTF