Protein Info for HMPREF1058_RS07415 in Phocaeicola vulgatus CL09T03C04

Annotation: family 20 glycosylhydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02838: Glyco_hydro_20b
  • amino acids 61 to 141 (81 residues), 49.6 bits, E=6.4e-17
• PF00728: Glyco_hydro_20
  • amino acids 144 to 249 (106 residues), 105.9 bits, E=2.9e-34

Best Hits

KEGG orthology group: None (inferred from 97% identity to bvu:BVU_4142)

Predicted SEED Role

"Beta-hexosaminidase (EC 3.2.1.52)" in subsystem Chitin and N-acetylglucosamine utilization or N-Acetyl-Galactosamine and Galactosamine Utilization (EC 3.2.1.52)

MetaCyc Pathways

• chitin degradation II (Vibrio) (3/6 steps found)
• chitin degradation III (Serratia) (3/7 steps found)
• peptidoglycan recycling I (6/14 steps found)
• peptidoglycan recycling II (2/10 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Glycosaminoglycan degradation
• Glycosphingolipid biosynthesis - ganglio series
• Glycosphingolipid biosynthesis - globo series
• Nucleotide sugars metabolism
• Other glycan degradation

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.52

Use Curated BLAST to search for 3.2.1.52

Sequence Analysis Tools

See I8ZPD6 at UniProt or InterPro

Protein Sequence (668 amino acids)

>HMPREF1058_RS07415 family 20 glycosylhydrolase (Phocaeicola vulgatus CL09T03C04)
MKRRFSSFIGMILVCAVTIAQTSISLLPKPQLYKDTGKNFTMGKVKLSTPVLRPEWEVFI
MNAGGEIVEHSSSVIEVELVPSIEEARLNRAEAYRLSVSNKRIKIEAVTEQGVYWAMQTL
RQLERKKGKRSSVAGCEIVDWPAFRIRGFMQDVGRSYISMEELKREIEILSRFKINVFHW
HLTENQAWRLESKIFPMLNDSVNTIRMPGKYYTLEEARDLVDFCKKHQVLLIPEIDMPGH
SAAFVRAFRHDMQSPEGMKILKLLLDEVCETFDVPYLHIGTDEVEFTNPHFVPEMVAYVR
SKGKKVISWNPGWHYKPGEIDMTHLWSYRGKAQPGIPAIDSKFHYLNHFDVFGDIVALYN
SRIYDQAEGSEDIAGTILALWHDRLIDNEWNLVIENGLYPNMLAIAERAWRGGGTEYFDG
LGTILPPEDTEAFKEFADFEKRMLWHKEHTFKGYPFAYVKQTNVKWNITDAFPNGGDMDK
VFPPEQELKDTYHYNGNTYGVRQAIGAGIYLRHVWGTFVPGFYADPKEDHTAYAYTWVYS
PKDQEVGLWAEFQNYSRSEMDLAPLQGKWDYKGSRIWINDREIMPPVWTATHQVKSNEIP
LGNENCVARSPLAVHLNKGWNKVFLKLPVGKFRMDQTRLVKWMFTAVFVTPDGERAAEGL
IYSPDKQK