Protein Info for HMPREF1058_RS07390 in Phocaeicola vulgatus CL09T03C04

Annotation: cyclically-permuted mutarotase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 375 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details TIGR03548: cyclically-permuted mutarotase family protein" amino acids 48 to 368 (321 residues), 356.6 bits, see alignment E=5.9e-111 PF13854: Kelch_5" amino acids 154 to 192 (39 residues), 26 bits, see alignment 1.8e-09 PF07646: Kelch_2" amino acids 207 to 255 (49 residues), 27.9 bits, see alignment 5e-10 PF01344: Kelch_1" amino acids 207 to 256 (50 residues), 28.8 bits, see alignment 2.1e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to bvu:BVU_4137)

Predicted SEED Role

"Sialic acid-induced transmembrane protein YjhT(NanM), possible mutarotase" in subsystem Sialic Acid Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I8ZPE0 at UniProt or InterPro

Protein Sequence (375 amino acids)

>HMPREF1058_RS07390 cyclically-permuted mutarotase family protein (Phocaeicola vulgatus CL09T03C04)
MIRKIIYGVYAILGMMTMAACSGQSDASEISLEKMHGFPTENTGFLKGVSALYAGVIEGN
LLIAGGCNFPDIPVADGGKKAYYRDIYIAPLSNDTAFEWKKIGQLPQAAAYGVTISTEKG
LICVGGTTATHSLSDVFLLSLQKDTLKRETLPSLPVTMDNMAGALVGHSLYIVGGNVNGI
PSSAMYMLDLSDLSGGWKRETDIPGEPRVQPVCVAQDGKLYVWGGFAPAVEGHQASLSVD
GYMYSPETKEWSSVATPYDAEGNEISLGGGMGTSFGEGMILCAGGVDKDIFLKALQGIYA
GKEYLSHPVEWYRFNRNLLLYHPQTDKWTTLGEYEQGARAGAVIVSQDGFHYIINGELKP
GIRTNEINRIKEKRR