Protein Info for HMPREF1058_RS07030 in Phocaeicola vulgatus CL09T03C04

Annotation: translation initiation factor IF-3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 198 TIGR00168: translation initiation factor IF-3" amino acids 12 to 173 (162 residues), 180.9 bits, see alignment E=7.6e-58 PF05198: IF3_N" amino acids 12 to 80 (69 residues), 98 bits, see alignment E=2.8e-32 PF00707: IF3_C" amino acids 87 to 172 (86 residues), 110.9 bits, see alignment E=2.3e-36

Best Hits

Swiss-Prot: 100% identical to IF3_BACV8: Translation initiation factor IF-3 (infC) from Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / NBRC 14291 / NCTC 11154)

KEGG orthology group: K02520, translation initiation factor IF-3 (inferred from 100% identity to bvu:BVU_4058)

Predicted SEED Role

"Translation initiation factor 3"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I8ZN32 at UniProt or InterPro

Protein Sequence (198 amino acids)

>HMPREF1058_RS07030 translation initiation factor IF-3 (Phocaeicola vulgatus CL09T03C04)
MKNDSLKGQHRINEQIRAKEVRIVGDDVESAVYPIAQALKMAEDHEADLVEISPNAVPPV
CRIIDYSKFLYQLKKRQKEQKAKQVKVNVKEIRFGPQTDDHDYNFKLKHAIGFLQDGDKV
KAYVFFKGRSILFKEQGEVLLLRFANDLEEYAKVEQMPLLEGKRMTISLAPKKAGSPKKA
ETDTAKKENPKKAVETKE