Protein Info for HMPREF1058_RS05175 in Phocaeicola vulgatus CL09T03C04

Annotation: MATE family efflux transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 453 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 49 to 76 (28 residues), see Phobius details amino acids 93 to 115 (23 residues), see Phobius details amino acids 134 to 154 (21 residues), see Phobius details amino acids 166 to 188 (23 residues), see Phobius details amino acids 194 to 214 (21 residues), see Phobius details amino acids 237 to 259 (23 residues), see Phobius details amino acids 265 to 285 (21 residues), see Phobius details amino acids 317 to 338 (22 residues), see Phobius details amino acids 358 to 376 (19 residues), see Phobius details amino acids 397 to 416 (20 residues), see Phobius details amino acids 422 to 440 (19 residues), see Phobius details PF01554: MatE" amino acids 22 to 181 (160 residues), 106.6 bits, see alignment E=1.1e-34 amino acids 244 to 404 (161 residues), 59 bits, see alignment E=4.8e-20 TIGR00797: MATE efflux family protein" amino acids 22 to 404 (383 residues), 172.5 bits, see alignment E=6.5e-55 PF14667: Polysacc_synt_C" amino acids 137 to 258 (122 residues), 47.6 bits, see alignment E=2e-16

Best Hits

KEGG orthology group: None (inferred from 100% identity to bvu:BVU_3780)

Predicted SEED Role

"conserved hypothetical protein, putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9IQV1 at UniProt or InterPro

Protein Sequence (453 amino acids)

>HMPREF1058_RS05175 MATE family efflux transporter (Phocaeicola vulgatus CL09T03C04)
MATSREMTSGRPFPLILNFAFPLLLGNLLQQTYSLMDAVIVGKFLGINALASVGASTSVV
FLILGFCNGCCGGFGIPVAQKFGARDYGMMRRFVAVSLQLAAVMSVVIAIVTSMFCSDIL
QMMQTPENILEDAYLYLLITFIGVPCTFFYNLLSSIIRALGDSKTPFWFLLFSTILNILL
DLFCILILDWGVAGAAVATVFSQGVSAVLCYLYMMRHFEILKGTPTEHKFRGALAKTLLY
IGVPMGLQFSITAIGSIMLQSANNALGTACVAAFTAAMRIKMFCMCPLESLGIAMATYSG
QNYGAGKPKRIWLGIKASVLMMVIYCGFMFVVLMLGARTFALLFVDPAEWEILKDTELFL
HISVSFFPVLGLLCILRYSIQGVGFTNLAMLSGVSEMIARIMVSLYAVPILGYLAVCFGD
PTAWIFAVIFLIPAFIYVYGRIKRMSTSGMVKY