Protein Info for HMPREF1058_RS04935 in Phocaeicola vulgatus CL09T03C04

Annotation: site-specific integrase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 366 PF02899: Phage_int_SAM_1" amino acids 94 to 163 (70 residues), 26.3 bits, see alignment E=1.1e-09 PF13495: Phage_int_SAM_4" amino acids 94 to 169 (76 residues), 58.3 bits, see alignment E=1.3e-19 PF00589: Phage_integrase" amino acids 190 to 350 (161 residues), 132.3 bits, see alignment E=2.5e-42

Best Hits

KEGG orthology group: K04763, integrase/recombinase XerD (inferred from 84% identity to bfr:BF1390)

Predicted SEED Role

"Phage integrase:Phage integrase, N-terminal SAM-like"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I8ZJB1 at UniProt or InterPro

Protein Sequence (366 amino acids)

>HMPREF1058_RS04935 site-specific integrase (Phocaeicola vulgatus CL09T03C04)
MDHVRKQRGSIVLYKEKRNGADYIRIEYADSEAVGILLSQDAEKTGENSACIPAAAFRLP
DFYDRYSPHAYIDYSRVYVRHPKPKREYVLPEGYLELLEQKRYSPSTIKTYRAYFSDFME
YHKGHNINRLKVADINKYILYLVNEKKISVSQQNMRINAIKFYYEQVKGGKRQYYGGITR
TKEYKSLPEVLSRNEVGRILSCLSNRKHRCMISLIYSAGLRRSELLNLTPKDIISKRMLV
RIMGKGRKCRYSLLSEKLLKELREDFKEYRPQKWLFEGETPGEPYSASALVKVLKEAATH
AGIKYRVHVHMLRHSFATHLLEQGTDLRTIQELLGHNDIKTTSIYLHVTSTHKSSIPNPL
DSLDDS