Protein Info for HMPREF1058_RS03955 in Phocaeicola vulgatus CL09T03C04

Annotation: AMP nucleosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01721: putative AMP nucleosidase
  • amino acids 2 to 258 (257 residues), 350.7 bits, E=2.3e-109
• PF01048: PNP_UDP_1
  • amino acids 49 to 222 (174 residues), 100.2 bits, E=6.3e-33

Best Hits

KEGG orthology group: K01241, AMP nucleosidase [EC: 3.2.2.4] (inferred from 100% identity to bvu:BVU_3313)

Predicted SEED Role

"AMP nucleosidase (EC 3.2.2.4)" in subsystem Purine conversions (EC 3.2.2.4)

MetaCyc Pathways

• adenosine nucleotides degradation III (1/1 steps found)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.2.4

Sequence Analysis Tools

See I8ZH24 at UniProt or InterPro

Protein Sequence (258 amino acids)

>HMPREF1058_RS03955 AMP nucleosidase (Phocaeicola vulgatus CL09T03C04)
MKTKEEIVANWLPRYTKRSLNDFGEYILLTNFNKYVELFADKFNVPVLGRDANMTSAHAE
GITIINFGMGSPNAAIIMDLLGAIQPKACLFLGKCGGIDRKNKLGDLILPIAAIRGEGTS
NDYYPPEVPALPAFMLQRAVSSAIRDHARDYWTGTVYTTNRRIWEHDEEFKKYLLKTRAM
CVDMETATLFTTGFYNHIPTGALLLVSDQPMIPEGVKTEKSDSIVTQQYVEEHVEIGIAS
LQMIIEEKKTVKHLKFDW