Protein Info for HMPREF1058_RS03685 in Phocaeicola vulgatus CL09T03C04

Annotation: Fic family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 429 PF13776: DUF4172" amino acids 2 to 83 (82 residues), 93.9 bits, see alignment E=6.1e-31 PF02661: Fic" amino acids 112 to 219 (108 residues), 62.7 bits, see alignment E=4.7e-21

Best Hits

KEGG orthology group: None (inferred from 82% identity to pmz:HMPREF0659_A6332)

Predicted SEED Role

"FIG00938511: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9TYJ4 at UniProt or InterPro

Protein Sequence (429 amino acids)

>HMPREF1058_RS03685 Fic family protein (Phocaeicola vulgatus CL09T03C04)
MYIHERDNWTDFRWDASQVSLLQELVCRKQGLLFGRLSSLGFDSKLRAMAENLTYDVVYS
SEIEGIRLNVDDVRSSIARRLGIENVKYTAPSHYIDSVVNVMLEAVQNYDQPLSKEKLCA
WQAAFFPSGFSEGRQIEVGKYRSNEEHIISGMFEREKIHYIAPSPDRVEGEMERFLAWFD
SEEPVSSVIRSAVTHFWFVSIHPFEDGNGRLARILSDMQLARGEKSDYRFYNISSQINKD
KNHYYDILEKMQHGDGDLTEWLVWYLQKLIDALDEAEAIVTSILNKSFFWQKASSIPMTE
RQTEMLNLFLDGYESKITSKTWASLAKCSKDTAIRDIQDLVEKNILVIDIPGAKRPSYSI
VYDAEDLTQFFADVTITEEKGIPYLCALFKGKKQIRERLLKLDAERYLKDDLPLSNLLGK
YCSYLMAGK