Protein Info for HMPREF1058_RS03230 in Phocaeicola vulgatus CL09T03C04

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 263 transmembrane" amino acids 10 to 30 (21 residues), see Phobius details amino acids 67 to 89 (23 residues), see Phobius details amino acids 101 to 125 (25 residues), see Phobius details amino acids 131 to 151 (21 residues), see Phobius details amino acids 183 to 205 (23 residues), see Phobius details amino acids 236 to 254 (19 residues), see Phobius details PF00528: BPD_transp_1" amino acids 78 to 253 (176 residues), 59.8 bits, see alignment E=1.5e-20

Best Hits

Swiss-Prot: 38% identical to POTC_ECOLI: Spermidine/putrescine transport system permease protein PotC (potC) from Escherichia coli (strain K12)

KEGG orthology group: K11070, spermidine/putrescine transport system permease protein (inferred from 100% identity to bvu:BVU_3554)

MetaCyc: 38% identical to spermidine preferential ABC transporter membrane subunit PotC (Escherichia coli K-12 substr. MG1655)
ABC-25-RXN [EC: 7.6.2.11, 7.6.2.16]; 7.6.2.11 [EC: 7.6.2.11, 7.6.2.16]

Predicted SEED Role

"Spermidine Putrescine ABC transporter permease component potC (TC_3.A.1.11.1)" in subsystem Polyamine Metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.11 or 7.6.2.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9TZI4 at UniProt or InterPro

Protein Sequence (263 amino acids)

>HMPREF1058_RS03230 ABC transporter permease (Phocaeicola vulgatus CL09T03C04)
MVKKILCQGYLWLLLLLLYAPIFIIMIYSFTEAKVLGNWTGFSTKLYSSLFVAGTHHSLT
NALVNTLSIAFIAATVSTLLGSITAIGIFNLRPRARKAISFVNNIPILNGDIIIGISLFL
LFVSLGIPQGYTTVVLAHITFCTPYVVLSVLPRLKQMNPNIYEAALDLGATPMQALRKVI
VPEILPGMISGFMLAVTLSIDDFAVTVFTIGNEGLETLSTYIYADARKGGLTPELRPLST
IIFVLVLVLLVIINRRAGKKKEV