Protein Info for HMPREF1058_RS02865 in Phocaeicola vulgatus CL09T03C04

Annotation: PQQ-binding-like beta-propeller repeat protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 818 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF16371: MetallophosN" amino acids 36 to 102 (67 residues), 54.6 bits, see alignment E=2.7e-18 PF00149: Metallophos" amino acids 116 to 292 (177 residues), 39.6 bits, see alignment E=2e-13 PF13360: PQQ_2" amino acids 474 to 565 (92 residues), 38.4 bits, see alignment E=2.9e-13 amino acids 579 to 732 (154 residues), 53.8 bits, see alignment E=5.6e-18 amino acids 639 to 806 (168 residues), 65.1 bits, see alignment E=2e-21 PF13570: PQQ_3" amino acids 518 to 557 (40 residues), 29.8 bits, see alignment 1.5e-10 amino acids 729 to 780 (52 residues), 20.5 bits, see alignment 1.4e-07 amino acids 781 to 816 (36 residues), 24.6 bits, see alignment (E = 6.9e-09) PF01011: PQQ" amino acids 540 to 566 (27 residues), 23.4 bits, see alignment (E = 9.3e-09) amino acids 762 to 796 (35 residues), 28.4 bits, see alignment (E = 2.4e-10)

Best Hits

KEGG orthology group: None (inferred from 99% identity to bvu:BVU_0400)

Predicted SEED Role

"FIG00408892: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I8ZHI5 at UniProt or InterPro

Protein Sequence (818 amino acids)

>HMPREF1058_RS02865 PQQ-binding-like beta-propeller repeat protein (Phocaeicola vulgatus CL09T03C04)
MKKTFLLSCLMLAAMPVMAAYTGHVYVDKNKNGVFDQSEKPLAGIKVSDGLNVVETAADG
SFTLPGHERERFIFITTPSGYKTFNRHYHKIEKKQSGYDFGLIPYSGRIRKDGSHRYIHI
TDTEIFNTENHADWVNNVRDYARNEQAAFIIHTGDICYEKGLKAHIKLMNTENMDCPVFY
CIGNHDLVKGKYGEELFESIYGPVYYSFDAGNVHYVVTPMPGGDHAPGYTSDDVCRWLKN
DLAHICPGTPVVVFNHDLLTYEDTFIFKSKNAGSINLNEYNLKAWVYGHWHINYMKKQGD
VYSVCTSSLDKGGIDHSTTAFRVMHVDSKGDFTSELRYTYLDKNICIASPAGVMASGVLP
VAVNVYSSVSPVREVLYTCLADGKPVLKNKRLLQSTDWSWNGELPLSHKYVGKELTLRVT
ARFNNGEIAEAESNFICRTEKAVPLFSADWDNLSGNAKHSAPVSAPLNLPLQLAWTNNVG
ANLYMTSPLIHKGKVIVASVDEDLKGAGHVYVLNGKDGTILWSCPVRNSIKNSIAVDSDI
VFAQDAQGFLYAIDTETGKLCWEKQLPVNGLPALIDGLVAGEGVVYAGTGKGLCAFEART
GKQLWKNEGWGQGEGTTSTLTLGNNLLVAGAQWNALYGNDAKTGEKLWAVSDNGLRNRGA
SPAMHGALLYLISDKSFFILEAATGKVIVRKPLPYNVDVTSTPLLTDKEIIFGSAQKGLI
ALDSETLEEKWTCPVGDALVYTCPYSRQPSATIETSAVWAGDIVYIAASDGTVYGINKED
GKVVWKHATGAPMFGSVALSGNALVVSDFGGNVYLFCK