Protein Info for HMPREF1058_RS02285 in Phocaeicola vulgatus CL09T03C04

Annotation: radical SAM protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 PF04055: Radical_SAM" amino acids 92 to 232 (141 residues), 59.2 bits, see alignment E=6.1e-20 TIGR04085: radical SAM additional 4Fe4S-binding SPASM domain" amino acids 323 to 405 (83 residues), 43 bits, see alignment E=2.4e-15

Best Hits

Predicted SEED Role

"Radical SAM"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I8ZGG3 at UniProt or InterPro

Protein Sequence (441 amino acids)

>HMPREF1058_RS02285 radical SAM protein (Phocaeicola vulgatus CL09T03C04)
MVESDYNYYTPYEGNIICMNGVTGTVFTVTKNEYDLMKKIMQNADLQGIYSELTHKLIKT
RFLTTNMDDEKEYLKALNKQVNNDGTWHLTLNPTQNCNFRCWYCYEKHPKGYMQPETVKR
IKCLATHIFEKGDTKHFVLSWFGGEPLLYFEKIIYPLSIFIKQLAEEHHVKFSNSITTNG
FFLTGSVIEKCKTIDLKKIQITLDGDKESHDKIRNQGGKPSFDKILQNSIALCNSCSDAV
IKLRINYNTDNIQHDFSEVLREIPENLRSRFFIQFQRIWQTYQNESNDEIVKRYLDENFF
KLKKEGFNLSVNTNYNKFGGISCYADRINYANINYDGNVYKCTAQDYTSETALGFLDENG
QIRWDKEKTQGIDKQAFFDNQVCLNCKYLAICGGPCFYAWWKCVRNKNNIECPNKKDKLD
IDLPLFIREYYLGRLKKKYCN