Protein Info for HMPREF1058_RS02185 in Phocaeicola vulgatus CL09T03C04

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 391 transmembrane" amino acids 24 to 46 (23 residues), see Phobius details amino acids 191 to 213 (23 residues), see Phobius details amino acids 235 to 259 (25 residues), see Phobius details amino acids 272 to 296 (25 residues), see Phobius details amino acids 308 to 330 (23 residues), see Phobius details amino acids 357 to 377 (21 residues), see Phobius details PF12698: ABC2_membrane_3" amino acids 26 to 376 (351 residues), 153.1 bits, see alignment E=5.4e-49

Best Hits

KEGG orthology group: K09686, antibiotic transport system permease protein (inferred from 99% identity to bvu:BVU_0261)

Predicted SEED Role

"ABC-type multidrug transport system, permease component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9TXA6 at UniProt or InterPro

Protein Sequence (391 amino acids)

>HMPREF1058_RS02185 ABC transporter permease (Phocaeicola vulgatus CL09T03C04)
MNNTVHNRIFRIARREVFRIATRPLYLFCMIIAPLFCYLFFTTLMWNGLPTDMPAGVVDL
DNTATTRSIIRNLDAFQQTKIIAHYPSFADARKAMQQGKIYAFYYIPKGTTEKALASRQP
KVSFYTNYSYLVAGSLLYKDQRTMSELAGGAIGRATLYAKGATEDQAMAFLQPIVIDSHV
LNNPWLNYSVYLSNTIIPGILMLLIFMTTVYTIGSEMKTNTQKEWMGMADNSITVALTGK
LLPQTVVFFVMATFYNVYLYGFLHYPCNSGILPMLFAGLLLVLASQAFGVFLFGLFTTVR
LALSTASLWGVISFSISGMSFPVMAMNPVLQALANLFPLRHYFLIYVDLALNGYPLIYVW
HSVVALMLFMLLPFFILKRLRTVLLHYVYIP