Protein Info for HMPREF1058_RS00870 in Phocaeicola vulgatus CL09T03C04

Annotation: DUF4982 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1001 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF02837: Glyco_hydro_2_N" amino acids 73 to 183 (111 residues), 53.7 bits, see alignment E=8.5e-18 PF00703: Glyco_hydro_2" amino acids 210 to 311 (102 residues), 55.8 bits, see alignment E=2.7e-18 PF02836: Glyco_hydro_2_C" amino acids 317 to 452 (136 residues), 29.1 bits, see alignment E=2.1e-10 PF16355: DUF4982" amino acids 633 to 690 (58 residues), 63.8 bits, see alignment 4e-21 PF18565: Glyco_hydro2_C5" amino acids 710 to 804 (95 residues), 62.9 bits, see alignment E=7.7e-21

Best Hits

KEGG orthology group: None (inferred from 100% identity to bvu:BVU_0162)

Predicted SEED Role

"Beta-galactosidase (EC 3.2.1.23)" in subsystem Galactosylceramide and Sulfatide metabolism or Lactose and Galactose Uptake and Utilization or Lactose utilization (EC 3.2.1.23)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.23

Use Curated BLAST to search for 3.2.1.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1001 amino acids)

>HMPREF1058_RS00870 DUF4982 domain-containing protein (Phocaeicola vulgatus CL09T03C04)
MRNKILLFLLTFIGISQIAAASSVRDKYNFNSEWLLYVGDIPEAKEVRFQDTDWKKVTLP
RPFNEDEAFRLSIEQLTDTVMWYRKHFRLPADSKNKKVFVEFEGVRQGADFYINGEYIGL
HENGAMAVGFDLTPYIKYGQENVMAVRIDNNWNYKERATGTKYQWSDRNFNANYGGIPKN
VWLHVTDKLYQTLPLYSNLKTTGVYIYAEDIRVKSRKAVVHAESEIKNEYNRDKKVAYKV
EVFDRDGKSIKSFEGTQTVVKPGETATLEASAEIDGLHFWSWGYGYLYTVKTSLWVDGRK
VDEVATRTGFRKTRFGKGMIWLNDRVIQMKGFAQRTSNEWPGVGMSVPAWLSDYSNGLMV
EDNANLVRWMHITPWKQDIESCDRVGLIQAMQAGDAEKDREGRQWEQRTELMRDAIIYNR
NNPSILFYECGNESISREHMIEMKAIRDKYDPHGGRAIGSREMLDIREAEYGGEMLYINK
SKHHPMWAMEYCRDEGLRKYWDEYSYPYHKNGEGNNSFRSAMTNKVQKKVDARAYNHNQD
SFTIENVIRWFDYWRERPGTGDRVSSGGVKIIFSDTNTHYRGVENYRRSGVTDAMRIPKD
PFYAHQVMWDGWVDIENPRIHIVGHWNYKEDVVKPVYVVSSAEKVELFLNGKSLGNGQRD
YHFLYTFKDVAFVPGKLEAVGYDKNGKECCRAELQTAGKPEQIKLSVIQSPKGWKADGAD
MVLLQVEVMDKDGRRCPLANDLIHFDVEGPAEWRGGIAQGKDNYILSKDLPVECGINRAL
IRSLTTPGTVRITAKADGLQSAEISLSSAPVEVKNGLSNYIPGDELEGRLTRGETPLTPS
YKDTKVDVNILSAVAGANQDEAIKSFDDNELSEWKNDGRLNSAWITYSLERAARVDEICM
KLTGWRLRSYPLEIYAGDELIWSGETEKSLGYIHLNVKPVLTNEITIRLKGASKEGDGFG
QIVEVAAPAAGELDLFKAKNGDKTNHELRIVEIEFKENLWQ