Protein Info for HMPREF1058_RS00865 in Phocaeicola vulgatus CL09T03C04

Annotation: rhamnogalacturonan acetylesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 547 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00657: Lipase_GDSL" amino acids 65 to 277 (213 residues), 45.4 bits, see alignment E=1.1e-15 amino acids 316 to 528 (213 residues), 31.8 bits, see alignment E=1.6e-11 PF13472: Lipase_GDSL_2" amino acids 68 to 274 (207 residues), 45.6 bits, see alignment E=1.2e-15 amino acids 319 to 496 (178 residues), 43.9 bits, see alignment E=4e-15

Best Hits

KEGG orthology group: None (inferred from 100% identity to bvu:BVU_0160)

Predicted SEED Role

"rhamnogalacturonan acetylesterase" in subsystem L-rhamnose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (547 amino acids)

>HMPREF1058_RS00865 rhamnogalacturonan acetylesterase (Phocaeicola vulgatus CL09T03C04)
MKGNKLCLCFLLAAGVGLGAHAQNKIAAPMKDVNQVVDNTLDSLNVARSARPVSGSSRKG
DNPVLFLVGNSTMRTGTLGNGNNGQWGWGYFEHEYFDENKITVENHALGGTSSRTFYNRL
WPDVLKGVRKGDWVIIELGHNDNGPYDSGRARASIPGIGKDSLNVTIKETGAKETVYTYG
EYMRRFIHDVKKKGAHPILMSLTPRNAWEDADSTIITRVNQTFGLWAKQVAKKARVPFID
LNDISARKFEKFGKEKVKYMFYLDRIHTSAFGARVNAESAAEGIRNYKGLELARYLKPVE
KDTVTGATRKKGNPVLFTVGDSTVKNADKDEKGMWGWGSVIHELFDTERISVENHAKAGR
SARTYLDEGRWDKIYHALQPGDFVLIQFGHNDAGDINTGKARAELPGSGNESKVFKMEKT
GSYQVVYSFGWYLRKFIMDVKEKGAVPIVLSHTPRNKFDNGEIERNTSSFGKWTREAAEA
AGAYFIDLNKISGDKLQDMGYNQGLRVVGTYFNHDHTHTSLKGARMNARSIADGLKATDC
PLKDFLK