Protein Info for HMPREF1058_RS00520 in Phocaeicola vulgatus CL09T03C04

Annotation: tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 229 TIGR03725: tRNA threonylcarbamoyl adenosine modification protein YeaZ" amino acids 4 to 218 (215 residues), 150.1 bits, see alignment E=4.2e-48 PF00814: TsaD" amino acids 35 to 154 (120 residues), 89.7 bits, see alignment E=1.4e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to bvu:BVU_1646)

Predicted SEED Role

"TsaB protein, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I9TU38 at UniProt or InterPro

Protein Sequence (229 amino acids)

>HMPREF1058_RS00520 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB (Phocaeicola vulgatus CL09T03C04)
MSCILHIETSTEACSVAVSEDGLAVFSKEDLKGPSHAVQLGVFVDEALSFVDSHGMPLDA
VAVSCGPGSYTGLRIGVSMAKGICYGRNLPLIGLPTLEVLCVPVLLHHDLPEDALLCPMI
DARRMEVYAAVYDRALGVKREIAADIVDEHSYLEFLNEHPVYFFGNGAAKCRGQITHPNA
HFIDDIRPLGKWMFPLAEKEMVRQNFKDVAYFEPFYLKEFVASKPKKLL