Protein Info for HMPREF1058_RS00045 in Phocaeicola vulgatus CL09T03C04

Annotation: SusC/RagA family TonB-linked outer membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 949 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 38 to 949 (912 residues), 673.8 bits, see alignment E=2.8e-206 PF07715: Plug" amino acids 52 to 156 (105 residues), 54.1 bits, see alignment E=1e-18

Best Hits

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I8ZB09 at UniProt or InterPro

Protein Sequence (949 amino acids)

>HMPREF1058_RS00045 SusC/RagA family TonB-linked outer membrane protein (Phocaeicola vulgatus CL09T03C04)
MRKNRLIIPALLAFLSMQGYAQELNDSITSGKPAKYSDEVVEIGYHKAQCLEESTSSIST
VYNEDFNKRSAKNIANSLFGYGTGLTTLQGSGRYADAEPTFFIRGLQSLSTNNPLILVDG
IERDITDVTPEEVETVTILKDAAAVAIYGHKGINGVVNITTKRGIYNTREIKFTYDHGFG
WQARKPKFVDSYSYANAMNEALANDGLTARYTQDELNAFRSGQYPYLYANVDWLGETYRD
MDATNIYNISFRGGASKFRYYAMANLTTNKGFIANPYMNDGYSTQDQYSRANLRTNLDID
LTEKTKLKLNVLGILSETRTPGANGQGGANLWDMIYTLPSAAFPARLENGTWGGSATWAG
TKNPLAVSQAAAYTKFHERTLFADMTLTQDLSSITPGLGASGMLSYDNYAQYWENHSKTF
VYGSNSVTAWENGVPSSTTYYTDGKESSMSSDAKCIAFTRVFNFAATLFYDKQINKDNKI
YSQLKWDYEYRNTKGTDQTWYRQNASFYTHYGYKDKYFADLSVVASASNKLAPGHQWSIS
PTVGLAWVMSKENFMKDLSWINFMKLRASFGIINTDRLPLDDDSEVTNYWEQTYGGGGYY
PFDTNYSVGTQSWSLGRLASLNSTHEKAYKYNLGLDASMFNGLDVSFDAYYERRSDIWVS
SSGHYSSVLGFTAPYENGGIVDSWGVEIGANYRKKIADITLNIGANFALAKNEIIEQMEE
PRMYDNLITTGKPLKQTYGMEVIGYFKDQADIENSPKQSFGDVKPGDIKYKDVNGDNIID
ANDKVAIGHSTTAPEIYYSFNLGAEWKGLGFDAMFQGTGRYSAVLNTKSLYWPLINNTTI
SQEYYDNRWTPENQDAKYPRLSSQSNENNYQTNTLWLADRSFLKLRSIELYYKFPQIWVK
KSKILSNAKIYVRGVDLLCFDKINIADPEVYGVTYPLTRSVVAGLTIGF