Protein Info for H281DRAFT_06524 in Paraburkholderia bryophila 376MFSha3.1

Annotation: cobaltochelatase CobN subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1271 TIGR02257: cobaltochelatase, CobN subunit" amino acids 1 to 1262 (1262 residues), 1619.8 bits, see alignment E=0 PF02514: CobN-Mg_chel" amino acids 140 to 1249 (1110 residues), 1357 bits, see alignment E=0

Best Hits

Predicted SEED Role

"CobN component of cobalt chelatase involved in B12 biosynthesis" in subsystem Coenzyme B12 biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MIT2 at UniProt or InterPro

Protein Sequence (1271 amino acids)

>H281DRAFT_06524 cobaltochelatase CobN subunit (Paraburkholderia bryophila 376MFSha3.1)
MHLLRTTPGGFVDDTQGVIRIDQRPADIVVLSSADTTLSLLASVFPRLGDGFPSVRLANV
TYLRQPASVDFYVEDVLQHARVVVVDHLGGEAYWPYGIEQVVALAERKQQTLAMFSGDLQ
EDPNLLARSTADADLCHQLWRYLREGGPQNAEAFLRCIAYRALGWGHEPAPPRALPAASL
YHPQRDTPTIADWQARWRHDAPVAAILFYKAHLQAANTAVFDALIEALDAQGVNPLPIAI
TSLKDAVSREVVQSLCSQHDAALVLNTTAFAASAIDDPEPLALAGDAPVLQVILSGGNRE
DWLKDNQGLNSRDIAMHIALPEVDGRIITRAISFKGLAYRCPHTEVDVVRYQPDRERVDF
IAELSRRWCRLRSLDNADKKLALILANYPMSEGRIGNGVGLDTPASVVGILSMLRDEGYR
VAAVPDNGDALLQKLTEGVTNDPVVRDLRPALQSFALADYLTHFNALPAEARNALNARWG
PPEHDPSVRRGRFMIAGWRCGHVFVGIQPSRSREQGDYASYHDAELVPPHAYLAFYFWLR
HQFGIDAVVHVGKHGNLEWLPGKSVALSDTCWPDLILGPMPHLYPFIVNDPGEGSQAKRR
TQAVIVDHLMPPLTRAESYGPLQDLERQVDEYYEALMVDPRRSKLLRRTILATIVEHKLH
EELSLSEPKGEDDEDALLTRVDAWLCELKEAQIRDGLHTFGQSPQAVQRRDTLLALARFP
VGDGQGCNAGLIDALARDLQIDHFFDPLSVDWSAAWTGPRPDILQQVSDAPWRHCGDTRE
RLELFAAEMLRSLCEPQARTDTDTSSALAKAPLPQAGRVIERLRNDVLPRLDACGTQEMT
HLRRGLEGRFVPPGPSGSPSRGRPDVLPTGRNFYSVDTRAVPTQAAWSLGLKSAQQLIER
HLQEHGDYPRAIGLSVWGTATMRTGGDDIAQALALLGVRPKWAPGSHRVTDFEIMPIEAF
DRPRIDVTLRVSGFFRDAFANVMHLFDAAVQAVAELDEPAELNPIRERVLRERDALIAHG
MDATEARKRAGWRVFSARPGAYGAGLQDMIDSQQWQTDADLANAYQAWGGYAYTQKNAGE
EARHAFGTRLAAMDVVLQNQDNREHDLLDSNDYYQFQGGMVAAVRHLAGNQPSVYHADHS
NPAAPRVRTLHEEIARVVRSRVVNPKWIDGVKRHGYKGASEIAATVDYLYGYDATARVVA
DHQYALVTDAYLNDADTREFLQRHNPHALHSICERLLEAMQRGLWQTPGDYRAQVEQHLL
ASEQQIEGMQS