Protein Info for H281DRAFT_06348 in Paraburkholderia bryophila 376MFSha3.1

Annotation: MFS transporter, AAHS family, 4-hydroxybenzoate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 452 transmembrane" amino acids 21 to 48 (28 residues), see Phobius details amino acids 60 to 79 (20 residues), see Phobius details amino acids 90 to 110 (21 residues), see Phobius details amino acids 116 to 137 (22 residues), see Phobius details amino acids 149 to 171 (23 residues), see Phobius details amino acids 177 to 197 (21 residues), see Phobius details amino acids 255 to 276 (22 residues), see Phobius details amino acids 295 to 315 (21 residues), see Phobius details amino acids 322 to 339 (18 residues), see Phobius details amino acids 345 to 370 (26 residues), see Phobius details amino acids 383 to 402 (20 residues), see Phobius details amino acids 408 to 431 (24 residues), see Phobius details PF07690: MFS_1" amino acids 30 to 306 (277 residues), 122.1 bits, see alignment E=3.9e-39 amino acids 262 to 446 (185 residues), 58 bits, see alignment E=1.2e-19 PF00083: Sugar_tr" amino acids 34 to 384 (351 residues), 78.6 bits, see alignment E=7.3e-26 PF06779: MFS_4" amino acids 46 to 213 (168 residues), 36 bits, see alignment E=8.2e-13

Best Hits

Swiss-Prot: 44% identical to PCAK_ACIAD: 4-hydroxybenzoate transporter PcaK (pcaK) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)

KEGG orthology group: K08195, MFS transporter, AAHS family, 4-hydroxybenzoate transporter (inferred from 93% identity to bug:BC1001_5135)

Predicted SEED Role

"4-hydroxybenzoate transporter" in subsystem Cinnamic Acid Degradation or Gentisare degradation or Phenylpropanoid compound degradation or Salicylate and gentisate catabolism or p-Hydroxybenzoate degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MMA0 at UniProt or InterPro

Protein Sequence (452 amino acids)

>H281DRAFT_06348 MFS transporter, AAHS family, 4-hydroxybenzoate transporter (Paraburkholderia bryophila 376MFSha3.1)
MNRSNAVNVQTFLNEHPFSPFQWLVFFMCFVIVLLDGFDTAAIGFIAPSLLAEWGIAKPA
LAPVLSAALFGLACGALVSGPLSDRLGRRGMLLGSVLLFGAACLGSAFSTSIEYLTVLRF
ITGVGLGAAMPNAVTMMGEYCPDSRRATVINLMFCGFPLGAAFGGFLAAWMIPHFGWRSV
LMLGGIAPLLLLVLLVIKMPESVRYMVANNQPVARIRTALSRISSEAAQADSFMMTETAP
QTGGKGAGVVLSRAYIVGSLMLWITYFMGLVIFYASINWMPILLKDAGLTPQRATLISAL
FPLGGVGAVVCGVLMDRFNANRIIAACYALTAVSVYFIGQAVGNVGALVFIVFVAGVLMN
TAQSSMPALAAAFYPTQGRGTGVAWMLGIGRFGGIAGSFLVAELARRHFTFAGIFATIAV
AGVIACIALLIKQAARPHVANASVPKAESFGH