Protein Info for H281DRAFT_06235 in Paraburkholderia bryophila 376MFSha3.1

Annotation: Phospho-N-acetylmuramoyl-pentapeptide-transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 389 transmembrane" amino acids 23 to 45 (23 residues), see Phobius details amino acids 66 to 91 (26 residues), see Phobius details amino acids 97 to 114 (18 residues), see Phobius details amino acids 134 to 152 (19 residues), see Phobius details amino acids 163 to 180 (18 residues), see Phobius details amino acids 190 to 211 (22 residues), see Phobius details amino acids 222 to 243 (22 residues), see Phobius details amino acids 256 to 279 (24 residues), see Phobius details amino acids 286 to 307 (22 residues), see Phobius details amino acids 312 to 334 (23 residues), see Phobius details amino acids 367 to 386 (20 residues), see Phobius details TIGR00445: phospho-N-acetylmuramoyl-pentapeptide-transferase" amino acids 38 to 389 (352 residues), 396.5 bits, see alignment E=5.3e-123 PF10555: MraY_sig1" amino acids 68 to 80 (13 residues), 26.3 bits, see alignment (E = 3.6e-10) PF00953: Glycos_transf_4" amino acids 99 to 307 (209 residues), 103.7 bits, see alignment E=1.1e-33

Best Hits

Swiss-Prot: 99% identical to MRAY_PARPJ: Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) from Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN)

KEGG orthology group: K01000, phospho-N-acetylmuramoyl-pentapeptide-transferase [EC: 2.7.8.13] (inferred from 99% identity to bxe:Bxe_A0483)

Predicted SEED Role

"Phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13)" in subsystem Peptidoglycan Biosynthesis (EC 2.7.8.13)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.8.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MEG3 at UniProt or InterPro

Protein Sequence (389 amino acids)

>H281DRAFT_06235  Phospho-N-acetylmuramoyl-pentapeptide-transferase (Paraburkholderia bryophila 376MFSha3.1)
MLLALAQWLQNDASFLRVFSYLTFRAVMATITALLIGLVCGPAVIRKLTAMKVGQAVRKD
GPQTHLVKSGTPTMGGVLILLGIAVATLLWADLTNRFIWIVILVTFGFGVIGWVDDYRKV
VYKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEASNVRVFDLFMAWVRSGLSMGLPARA
DLMLPFVKSISYPLGVWGFIVLTYLVIVGASNAVNLTDGLDGLVIMPVVLVGASLGVFAY
VMGSSVYSKYLLFPHIAGAGELLIFCSAMGGAGLAFLWFNTHPAQMFMGDVGALALGGAL
GTVAVIVRQEIVLFIMGGIFVAETLSVMLQVAWFKFTKRRFGEGRRLFKMAPLHHHFELS
GWKETQVVVRFWIITLMLCLFGLSTLKLR