Protein Info for H281DRAFT_06225 in Paraburkholderia bryophila 376MFSha3.1

Annotation: Anaerobic selenocysteine-containing dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 625 PF00384: Molybdopterin" amino acids 6 to 409 (404 residues), 129.4 bits, see alignment E=1.8e-41 PF01568: Molydop_binding" amino acids 509 to 618 (110 residues), 79.2 bits, see alignment E=2.4e-26

Best Hits

KEGG orthology group: None (inferred from 91% identity to bug:BC1001_3122)

Predicted SEED Role

"Anaerobic dehydrogenases, typically selenocysteine-containing" in subsystem Anaerobic respiratory reductases

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (625 amino acids)

>H281DRAFT_06225 Anaerobic selenocysteine-containing dehydrogenase (Paraburkholderia bryophila 376MFSha3.1)
MKRIGRKGEGHFEPISWSEAFELGAKHLSEIAQRAPEAILPYSYAGTMGLVQGDSIAQRF
FHKLGASQLDRTICAAAGAAGLKYTYGAGIGMLTEFFDESEVILIWGSNPIASNLHFWTR
AQQAKRHGARLIAIDPYRSLTAEKCHQHIALKPGTDGALALGMMNVLISEDLLDHAYIAA
HTLGFDELKARALQYSPSRVAEICGIDEQVIVDLACLYGSTKKAAIRLNYGLQRVRGGGN
AVRAIACLPSLTGAWRERAGGALLSSSGWAPVDTHALQRPDLMPGWPTRPSRVINMNAIG
DALLHPGDATFGPKIEAIVVYNSNPVAVAPDSERVAAGFAREDLFTIVLEHFQTDTADYA
DLLLPATTQLEHLDVHKSYGHTHVMVNLPAIPPVGDARPNTEIFRGLARQMGLDEPSLFE
SDETVARSALRWQDKTLEGVDWESLKRVGWAKLNLPDAPFAEGGFRTPSGKCEFYSERLA
QQGLDPLPDYVPPYESAESAPELAARYPLAMISPPARNFLNSTFVNVESLRSTEGEPHLD
IHPSDAGSRDIVDGDQVRIFNDRGSMQARARVTDRARQGLVVGLSIWWKKLAPDGRNANQ
VTSQALTDLGGSATFYDCLVQVERV