Protein Info for H281DRAFT_06211 in Paraburkholderia bryophila 376MFSha3.1

Annotation: transcriptional regulator, propionate catabolism operon regulatory protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 635 TIGR02329: propionate catabolism operon regulatory protein PrpR" amino acids 14 to 633 (620 residues), 656.5 bits, see alignment E=1.5e-201 PF06506: PrpR_N" amino acids 38 to 202 (165 residues), 160.2 bits, see alignment E=1.5e-50 PF00989: PAS" amino acids 208 to 258 (51 residues), 28.5 bits, see alignment 5.4e-10 PF00158: Sigma54_activat" amino acids 331 to 498 (168 residues), 223.1 bits, see alignment E=7.4e-70 PF14532: Sigma54_activ_2" amino acids 331 to 502 (172 residues), 73.8 bits, see alignment E=6.8e-24 PF07728: AAA_5" amino acids 355 to 472 (118 residues), 24.3 bits, see alignment E=1.1e-08 PF02954: HTH_8" amino acids 604 to 634 (31 residues), 31.6 bits, see alignment (E = 4.5e-11)

Best Hits

Predicted SEED Role

"Propionate catabolism operon regulatory protein PrpR" in subsystem Methylcitrate cycle

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (635 amino acids)

>H281DRAFT_06211 transcriptional regulator, propionate catabolism operon regulatory protein (Paraburkholderia bryophila 376MFSha3.1)
MKQTTKSQFAVSGRRPRIWAIGISRLRELYRDLASSYDDVADIRLLERGFDGALEAISAA
GAERPDVIVSAGANGNYVKSRTDIPVVLVSATGFDVMQALGRARRESEKIALVMHGEMPT
EASRFLAAFGFDIVTMCYATTQDAENCVLDLRDAGVQVVVGPGLVTELADNFGMRSVFLY
SQGSVRTALDNALNLARAVRAEGMRRRRLDQVLANLRDGVVALDEAGRVEAISGKMASIL
GVPASQAVGKPLAELSPEVASAVPRMSGEASETINGITYAVHRHEWDEAGQGTGAVVTFV
ESLALQRMNNSLRSGQRVRQFTARYTIDDLLGNSNVIKKIRGRVRQYAASDATTLVTGAT
GTGKEIVAQSIHNLSARRRHAFVAINCGAFPDTLLESELFGYEDGAFTGARRGGKMGLIE
SAHQGTLFLDEIAEMPLALQSRLLRVIQEREVVRLGSTDPVKVDVRIITATHGALKARVD
EGTFRADLFYRVNVLTIEMPPLSERLEDLPLLARHLLKHMRPNWTSSEIDTSLQPILGLL
TGYAWPGNVRELYNVMERLALALPAPGRSIDVEQLCELMPEMTELAHPMPLKGSGQRHEI
DRVRKVLTSFDGDRDKTCEVLGISRTTLWRKLNQR