Protein Info for H281DRAFT_06095 in Paraburkholderia bryophila 376MFSha3.1

Annotation: D-amino-acid dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 411 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details PF01266: DAO" amino acids 4 to 391 (388 residues), 186.6 bits, see alignment E=2e-58 PF13454: NAD_binding_9" amino acids 5 to 90 (86 residues), 28.7 bits, see alignment E=2.4e-10 PF13450: NAD_binding_8" amino acids 6 to 32 (27 residues), 23.3 bits, see alignment (E = 1.3e-08)

Best Hits

KEGG orthology group: K00285, D-amino-acid dehydrogenase [EC: 1.4.99.1] (inferred from 85% identity to bvi:Bcep1808_6420)

Predicted SEED Role

"D-amino acid dehydrogenase small subunit (EC 1.4.99.1)" in subsystem Pyruvate Alanine Serine Interconversions or Respiratory dehydrogenases 1 (EC 1.4.99.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.4.99.1

Use Curated BLAST to search for 1.4.99.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MMJ2 at UniProt or InterPro

Protein Sequence (411 amino acids)

>H281DRAFT_06095 D-amino-acid dehydrogenase (Paraburkholderia bryophila 376MFSha3.1)
MSEIAIVGAGFIGLASAASLMRDGHRVTIFDPSGVGQGASFGNAGTFAHYACIPVNNPSV
FRDLPRYLFSGDSPFRLRYQYLPHLVPWLAHFMMSSLPRRYEASAGALAALLAQAQEGYA
PLLANAELARFVRSRECLYLYSSAASFNAARPALDLRKKLGVIFDVLGGNDIRALEPSLA
PIFERGVLFSDSWHFSDPQGFLQALFEQLAAQGLTLQRSTVSAVQPSGDGASVTADGVTR
RFGHVVIATGARSAQFARQCGDVVPLDTERGYHVRYPGAQQLISRPVGWAERGFYMTPMS
DGIRVAGTVELGGFSDTRNRSLLDLLTFSSRRALPLLEKPDSSWLGFRPTLPDGVPVLAR
SRASERVIYAFGHQHLGLTLAGVSGRIVADLVARRAPPLDLAPYAATRFGI