Protein Info for H281DRAFT_06090 in Paraburkholderia bryophila 376MFSha3.1

Annotation: N-ethylmaleimide reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 404 PF00724: Oxidored_FMN" amino acids 22 to 365 (344 residues), 275.1 bits, see alignment E=4.7e-86

Best Hits

KEGG orthology group: K10680, N-ethylmaleimide reductase [EC: 1.-.-.-] (inferred from 93% identity to bpy:Bphyt_5482)

Predicted SEED Role

"NADH:flavin oxidoreductases, Old Yellow Enzyme family"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.-.-.-

Use Curated BLAST to search for 1.-.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MKP3 at UniProt or InterPro

Protein Sequence (404 amino acids)

>H281DRAFT_06090 N-ethylmaleimide reductase (Paraburkholderia bryophila 376MFSha3.1)
MPDTETTFAAAGQHDEQIPLRKLFEPVKVGPYNLRHRAVMAPLTRSRASRPGNIPSQLNA
CYYAQRASAALIISEATQVSMQGQGYAWTPGIHSREQVEGWRLVANAVHEAGGLMFMQLW
HVGRISHPSLQPDEMLPVAPSALQPKAEAFIENERGEGVLAPCVTPRALQIEEMPYLVRQ
YFRGARNAKAAGMDGVEVHAANGYLLDQFLLSGTNRRTDEYGGSSERRAKLLFEVIETVC
EVWGPERVGVRLSPLGTFNDMHDDDPEATFSYVIEKLNRYRLAYLHIVNPALAATGEDGT
FTERAKRMSEMIRRTYRGVLMVAGGFDGSSAERWLEDGNADLIAFGRPFIANPDLPERLR
LHAPLNSPDPSTFYGGGERGYTDYPSLAQERGEAPRSVIDGRWR