Protein Info for H281DRAFT_06049 in Paraburkholderia bryophila 376MFSha3.1

Annotation: trehalose synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1153 TIGR02456: trehalose synthase" amino acids 42 to 578 (537 residues), 928.2 bits, see alignment E=1.4e-283 PF00128: Alpha-amylase" amino acids 65 to 418 (354 residues), 256.3 bits, see alignment E=9.3e-80 PF16657: Malt_amylase_C" amino acids 497 to 575 (79 residues), 88.2 bits, see alignment 4.7e-29 TIGR02457: putative maltokinase" amino acids 595 to 1120 (526 residues), 615.5 bits, see alignment E=8.7e-189 PF18085: Mak_N_cap" amino acids 626 to 681 (56 residues), 24.4 bits, see alignment 7.8e-09

Best Hits

KEGG orthology group: K05343, maltose alpha-D-glucosyltransferase [EC: 5.4.99.16] (inferred from 71% identity to bac:BamMC406_6321)

Predicted SEED Role

"Trehalose synthase (EC 5.4.99.16)" in subsystem Trehalose Biosynthesis (EC 5.4.99.16)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 5.4.99.16

Use Curated BLAST to search for 5.4.99.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MKE7 at UniProt or InterPro

Protein Sequence (1153 amino acids)

>H281DRAFT_06049 trehalose synthase (Paraburkholderia bryophila 376MFSha3.1)
MKRDDPSQGTSEAQASTATATATKARARRRGKPATLSDDPLWYKDAIIYQVHIKSFFDAN
NDGVGDFPGLIAKLDYIAELGVNAIWLLPFYPSPRRDDGYDIADYRNVHPDYGQLSDVKR
FIQEAHARGIRVITELVINHTSDQHPWFQRARRAKPGSNHRNFYVWSDTDQKYQETRIIF
IDSEPSNWTHDPVAGAYYWHRFYSHQPDLNFDNPAVLREVLQIMRFWLDMGIDGLRLDAV
PYLVEREGTNNENLPETHAILKKIRATIDAEYPNRMLLAEANQWPEDVKEYFGDEDECHM
AFHFPLMPRIYMSIASEDRFPITDIMRQTPDLAETNQWAIFLRNHDELTLEMVTDSERDY
LWNTYASDRRARLNLGIRRRLAPLMERDRRRIELINSLLLSMPGTPVIYYGDELGMGDNI
HLGDRDGVRTPMQWSSDRNGGFSRADPEQLVLPPVMGSLYGFDAVNVEAQSRDPHSLLNW
TRRMLATRRAKQTFGRGTIRFLKPENRKILAYLREMPNEPPILCVANLSRAPQAVELDLS
EFNGSVPIEMTADSVFPPIGQLTYLLTFPPYGFLWFMLCPGGQRPTWSQAHPEPLPEFVT
IVIREGQVGPTPENVRLLESEVLPSWLSRRRWFASKDQKMHAVRLAALTTIPNGGFAFTE
IEADVGDHTERYVVPIAITWGGETTTPLFLQLALARVRRGRNVGHLTDAFALPIFAHGVM
RKLRERAVIPTVQKSEIRFIPTERFAELENLGERPEIRWLAAEQSNSSLIIADAAVLKLV
RRLVSGIHPEAEISRYLTQLGYANTAPLFGEVVRVDPEGVPHTLAILQGYVDNQGDAWNW
SLDHLRRSVDELAIAVDTDASSTPDRGNETLLLEGYSSLAGIIGRRLGQLHVALASPTDD
PAFAPEQASAEQVKAWVDGTQSMLASALDLLAPRVEQMLDAETKALAKSLVDRRAALVEA
VNKLVSPDTQAQRIRIHGDFHLGQVLVAQGDAYLIDFEGEPARSLEERRQKSSPLRDVAG
LMRSLSYASAAAQSTMESAPQQTADRKRSLFDRFRVQATETFLKEYRAATAEAPTPLVAP
EAEQALLDLFLIEKAAYEIRYEAANRPAWLSLPVRGLAALAGRLLGDKTTSHDSSTQAQD
AATPPHPAEGDYE