Protein Info for H281DRAFT_05957 in Paraburkholderia bryophila 376MFSha3.1

Annotation: Predicted metal-dependent hydrolase, TIM-barrel fold

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 331 PF04909: Amidohydro_2" amino acids 14 to 324 (311 residues), 106.8 bits, see alignment E=8.9e-35

Best Hits

KEGG orthology group: None (inferred from 85% identity to bph:Bphy_6032)

Predicted SEED Role

"L-fuconolactone hydrolase" in subsystem L-fucose utilization temp

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (331 amino acids)

>H281DRAFT_05957 Predicted metal-dependent hydrolase, TIM-barrel fold (Paraburkholderia bryophila 376MFSha3.1)
LRKEPVLEPELPIVDAHHHLWDRQTGRYLADEFRNDVASGHRVVSTVYVQCRSMLREDGP
EAMKPVGEVEFANGIAAMSASGAYGRTRCCEAIVGGVDLTLGAELDAVLEAMLQVSGGRL
RGIRNPLAWHASPEVSSSPVTPPRDLMANPAYRQGVRALGRFDLSLDAWVYHTQLDDLYE
LARAADRVTVVIDHFGGPLGVGPHAGQRAAVRAEWQQKLARLASLPNTRIKLGGAGMNVF
GFDFAAREVPPSSEELAFAWRPYFDTCVELFGVNRCMFESNFPVDKGMFSYGVLWNAFKR
LASAMSANEKAALFSRTAAATYRLAIAGDNT