Protein Info for H281DRAFT_05929 in Paraburkholderia bryophila 376MFSha3.1

Annotation: Pimeloyl-ACP methyl ester carboxylesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00561: Abhydrolase_1
  • amino acids 11 to 243 (233 residues), 56.9 bits, E=2.5e-19
• PF12697: Abhydrolase_6
  • amino acids 12 to 249 (238 residues), 67.5 bits, E=2.8e-22

Best Hits

KEGG orthology group: None (inferred from 87% identity to bxe:Bxe_B1132)

Predicted SEED Role

"Alpha/beta hydrolase fold (EC 3.8.1.5)" (EC 3.8.1.5)

MetaCyc Pathways

• 1,2-dichloroethane degradation (3/4 steps found)
• γ-hexachlorocyclohexane degradation (6/11 steps found)

KEGG Metabolic Maps

• 1,2-Dichloroethane degradation
• 3-Chloroacrylic acid degradation
• Naphthalene and anthracene degradation
• gamma-Hexachlorocyclohexane degradation

Isozymes

Compare fitness of predicted isozymes for: 3.8.1.5

Use Curated BLAST to search for 3.8.1.5

Protein Sequence (262 amino acids)

>H281DRAFT_05929 Pimeloyl-ACP methyl ester carboxylesterase (Paraburkholderia bryophila 376MFSha3.1)
MPYVEAGEGELLLFVHGSLCDYRYWQPQLAGLSKHYRCVAVSLTHYWPMTDTRPDAPFSW
SAHADQVAQFIERFGVGAAHVVGHSRGGCVAFHSARRYPQHIRTLTLADPGGPLQIAGRP
PASVPETVNALRARAAQLIESGDVEAGLQLFVDSVSRPGFWAMSTPAFRRMATDNAATLP
LQLRDPLPPYVPQEAADVRCPVLLIDGEKSPEMFRRTAAALQSWLPDARRETVRGASHGM
NLAHPSAFNRYIDEFIRATNAR